摘要
富含亮氨酸重复序列(leucine-rich repeat,LRR)结构域15(LRR containing 15,LRRC15)蛋白是LRR的超家族成员之一。在医学领域,LRRC15蛋白不仅参与寄生虫、病毒等病原体感染,在抗肿瘤及类风湿性关节炎的治疗中也发挥作用,还对细胞自噬、干细胞成骨化和毛囊真皮乳头细胞特性变化起到调节作用。文中就LRRC15蛋白在医学领域中的研究进展做一综述。
The leucine-rich repeat(LRR)containing 15(LRRC15)protein is one of the members of the LRR superfamily.In the medical field,LRRC15 protein not only participates in parasitic,viral and other pathogen infections,but also plays a role in anti-tumor and rheumatoid arthritis treatment.It also regulates cell autophagy,stem cell ossification,and changes in hair follicle dermal papilla cell characteristics.This article reviews the research progress of LRRC15 protein in the medical field.
作者
余顺甫
穆倩倩
孙晓晴
周必英
Yu Shunfu;Mu Qianqian;Sun Xiaoqing;Zhou Biying(Department of Parasitology,Zunyi Medical University,Zunyi 563000,China;Clinical Laboratory,Liupanshui Third People's Hospital,Liupanshui 553000,China)
出处
《中华地方病学杂志》
北大核心
2024年第11期942-946,共5页
Chinese Journal of Endemiology
基金
国家自然科学基金(82460402、81960378)
