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血清降钙素原联合肝素结合蛋白在非感染重症监护室患者医院感染预测中的价值

Value of Serum Procalcitonin Combined with Heparin Binding Protein in Predicting Nosocomial Infection in Patients in Non-infectious Intensive Care Unit
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摘要 目的探究血清降钙素原(PCT)联合肝素结合蛋白(HBP)在非感染重症监护室患者医院感染预测中的价值。方法选取2022年5月至2024年5月期间南京鼓楼医院集团宿迁医院重症监护室收治的68例非感染患者。基于最终是否出现院内感染分为感染组(n=27)和与非感染组(n=41)。两组均进行血清PCT、HBP单独及联合检测,比较检测结果,分析其对医院感染的预测价值。结果感染组PCT及HBP水平较非感染组更高,P<0.05;PCT与HBP联合检测对医院感染的诊断效能均较单独检测更高,P<0.05。结论PCT联合HBP在非感染重症监护室患者医院感染预测中具有较高的应用价值,诊断的准确性、灵敏度及特异性均较高,有利于避免误诊和漏诊发生,及时发现患者的感染情况。 Objective:To Objective To explore the value of serum procalcitonin(PCT)combined with heparinbinding protein(HBP)in predicting nosocomial infection in patients in non-infected intensive care unit.Methods:From May 2022 to May 2024,68 non-infected patients admitted to the intensive care unit of Suqian Hospital of Nanjing Gulou Hospital Group were selected.Based on whether there was nosocomial infection in the end.They were divided into infection group(n=27)and non-infection group(n=41)based on whether nosocomial infection finally occurred.Both groups were tested for serum PCT and HBP separately and jointly.The test results were compared and their predictive value for nosocomial infection was analyzed.Results:The levels of PCT and HBP in infected group were higher than those in uninfected group,P<0.05.The diagnostic efficiency of PCT combined with HBP was higher than that of single detection,P<0.05.Conclusion:PCT combined with HBP has high application value in the prediction of nosocomial infection in patients in non-infectious intensive care unit,and the accuracy、sensitivity and specificity of diagnosis are high,which is conducive to avoiding misdiagnosis and missed diagnosis and finding the infection of patients in time.
作者 吉健 林爱华 Ji Jian;Lin Aihua(Department of Critical Care Medicine Suqian Hospital Nanjing Gulou Hospital Group,Suqian Jiangsu 223800,China)
出处 《生命科学仪器》 2024年第6期62-63,66,共3页 Life Science Instruments
关键词 血清降钙素原 肝素结合蛋白 重症监护室 医院感染 Serum procalcitonin Heparin binding protein Intensive care unit Hospital infection
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