摘要
To the Editor,Systemic lupus erythematosus(SLE)is a chronic autoimmune disease characterized by the production of autoantibodies against self-antigens,leading to widespread inflammation and multi-organ involvement.It can affect almost all organ systems,resulting in various clinical manifestations and numerous complications.1 Skin and mucosal lesions are observed in most patients with SLE.Typical manifestations include the characteristic butterflyshaped facial erythema,subacute cutaneous lupus,and chronic cutaneous lupus erythematosus,with other forms presenting as lupus panniculitis,chilblain lupus erythematosus,and discoid lupus erythematosus.2 Here,we report a case of a patient with persistent facial butterfly erythema that did not respond to standard treatments.
基金
supported by a grant from the Municipal School Cooperative Research Special Project(Sichuan North Medical College)in Nanchong,Sichuan Province,Grant/Award Number:19SXHZ0140.