摘要
目的 :研究光动力抑癌作用机制。方法 :采用MTT法检测光动力作用后人膀胱癌细胞株BIU -87增殖代谢活性。结果 :光动力实验组吸光密度值 (0 .1683± 0 .0 3 3 7)显著低于实验对照组 (0 .5 12 8± 0 .0 3 82、0 .7775± 0 .0 93 2、0 .72 2 3± 0 .0 3 5 5、0 .72 10± 0 .0 3 69) (P <0 .0 1)。结论 :光动力作用降低了人膀胱癌细胞株BIU -87的增殖代谢活性 ,这可能是其抑癌作用机制之一。
Objectives: To study on mechanisms of photodynamic inhibitory action on cancer.Method:The proliferating and metabolic status of BIU-87 cells post photodynamic therapy was determined with MTT assay.Results: At the wavelength of 490nm,the OD value post photodynamic therapy was obviously lower than that of the controls(0.1683±0.0337vs 0.5128±0.0382?0.7775±0.0932?0.7223±0.0355?0.7210±0.0369,p<0.01).Conclusion: Photodynamic action might significantly inhibit the proliferating and metabolic activity of BIU-87 cells,which is one of the mechanisms of photodynamic inhibitory action on cancer.
出处
《激光杂志》
CAS
CSCD
北大核心
2002年第6期74-75,共2页
Laser Journal
基金
重庆大学光电工程学院教育部光电技术开放基金资助
