摘要
目的探讨外伤性弥漫性脑萎缩的临床特征和形成机制。方法回顾性分析根据头部CT检查诊断的外伤性弥漫性脑萎缩18例,并和同期无脑萎缩的脑外伤病人100例进行比较。结果18例弥漫性脑萎缩病人的入院时GCS和脑萎缩发生时的GOS分别为6.3±2.9和3.39±0.70,明显低于对照组的10.5±3.4和4.67±0.59(P<0.01);手术治疗、去骨瓣减压、术后脑水肿的比率均明显高于对照组(P<0.01)。结论重度脑外伤可导致外伤性弥漫性脑萎缩,其发生机理可能为原发的神经元和轴突损伤以及继发的外伤后脑缺血性损害。
Objective To investigate the clinical features and mechanisms of post-traumatic diffuse cerebral atrophy.Methods 18cases of post-traumatic diffuse cerebral atrophy diagnosed upon CT examination were retrospectively analyzed and compared with100cases of head injury without post-traumatic cerebral atrophy at the same period.Results The Glasgow Coma Scale on admission and the Glasgow Outcome Scale when cerebral atrophy occurring were6.3±2.9and3.39±0.70respectively in the patients with cerebral atrophy,significantly lower than10.5±3.4and4.67±0.59respectively(P<0.01)in the compared patients;the incidence of operation,decompressive craniectomy,post-operative cerebral edema were higher than that in the compared patients.Conclusion Severe head injury can induce post-traumatic diffuse cerebral atrophy which may result from primary neural and axonal injuries and secondary ischemic damage to the brain.[
出处
《浙江创伤外科》
2002年第6期351-352,共2页
Zhejiang Journal of Traumatic Surgery
