摘要
目的 :研究多器官功能障碍综合征 (MODS)病人低白蛋白血症的临床特点。 方法 :选择 80例APACHE Ⅱ评分为 17～ 18分的MODS病人 ,分为腹腔感染组和非腹腔感染组 ,动态监测其血清白蛋白浓度 ,对结果进行统计学处理。 结果 :80例MODS病人低白蛋白血症的发生率为 73 8% ,其中腹腔感染组发生率为 97 0 % ,最低值发生于第 2天 ,为 (2 4± 3.5 ) g/L ,非腹腔感染组的发生率为 5 7.4 % ,最低值发生于第 7天 ,为 (35± 2 .9)g/L ,二者无论在低白蛋白血症的发生率 ,还是最低值发生时间及水平上的差异均非常显著 (P <0 .0 1) ;发生低白蛋白血症病人的病死率为 4 9 1% ,明显高于未发生低白蛋白血症者 (2 3.8% ,P <0 .0 5 )。发生低白蛋白血症的MODS病人中 ,腹腔感染组病死率为 5 9.4 % ,明显高于非腹腔感染组 (37.0 % ,P <0 .0 5 )。 结论 :危重病人低白蛋白血症的发生率较高 ,合并腹腔感染的病人较无腹腔感染者无论在低白蛋白血症的发生率、发生时间、降低程度都更明显 ,且降低的程度与预后呈明显相关。
Objectives:To study the clinical features of multiple organ dysfunction syndrome(MODS) complicated with hypoalbuminemia. Methods:80 cases of MODS whose APACHE Ⅱ was from 17 to 18 were selected and devided into two groups according to existance of peritoneal infection or not. Results:The occurrence rate of hypoalbuminemia was 73.8% in the 80 cases. The rate was 97.0% in the group complicated with peritoneal infection,with the lowest level occurring on the second day and being (24± 3.5 )g/L, and 57.4% in the group without peritoneal infection,with the lowest level occurring on the seventh day and being (35±2.9)g/L.There were very marked differences between the two groups( P < 0.01 ).The mortality rate of the patients with hypoalbuminemia was 49.1%,being much higher than that in the cases without hypoalbuminemia(23.8%)( P <0.05). Conclusions:The occurrence rate of hypoalbuminemia is higher in the severe patients.There are marked differences in occurrence rate,occurrence time,and decreasing level of hypoalbuminemia between the group complicated with peritoneal infection and the group without peritoneal infection.The decreasing level of plasma albumin correlates closely with the prognosis of the patients with MODS.
出处
《肠外与肠内营养》
CAS
2002年第4期232-234,共3页
Parenteral & Enteral Nutrition
