摘要
DNA微点阵 (DNA芯片 )技术已经被广泛应用于基因表达分析、比较基因组学、DNA序列变异分析和基因分型等多方面的研究。随着越来越多的微生物种类完成全基因组测序 ,在微生物生理、致病机制、流行病学、生态学、系统发育学、途径工程、发酵最优化等研究领域中 。
DNA microarray or DNA chip technology has been explored for profiling gene expression, comparing genomic contents, analyzing DNA sequence variations, and genotyping, etc . With the increasing availability of complete microbial genomes, DNA microarray technology is destined to become a common tool in many areas of microbiological research, including microbial physiology, pathogenesis, epidemiology, ecology, phylogeny, pathway engineering, and fermentation optimization.In this article,the current advances in microbiological research based on DNA microarray technology are reviewed.
出处
《军事医学科学院院刊》
CSCD
北大核心
2002年第4期294-300,共7页
Bulletin of the Academy of Military Medical Sciences
基金
全军医药卫生科研基金课题 (0 1L0 2 9)