摘要
目的 探讨乙肝病毒 (HBV)感染在烹饪专业大学生这个特定群体中的感染状况 ,为制定乙肝预防对策提供科学依据。方法 对 2 64名烹饪工艺系大学生进行HBV血清流行病学调查 ,并对其中 16例乙肝表面抗原 (HBsAg)携带者的HBV血清感染标志作了 3年的动态追踪观察。全部受检者首先用反向间接血凝法 (RPHA)测定HBsAg ,阳性者则用酶联免疫吸附试验 (ELISA)复查其它感染标志。用改良赖氏法测肝功 (ALT)。结果 HBsAg累计平均携带率为 6 3 0 % ,各年级阳性率差异有非常显著性意义。 (χ2 =12 0 6 P <0 0 0 5 )。HBsAg乙肝e抗原 (HBeAg)或乙肝核心抗体 (抗 -HBc)同时阳性血清占HBsAg阳性血清份数的 12 77%。 结论 对烹饪专业大学生定期进行健康检查 ,并同时开展HBsAg及其它HBV感染标志的动态监测 ,加强对具传染性检出者的卫生管理及门诊随访 ,在乙肝传染源管理中具有一定的指导意义。在制定今后的乙肝预防策略时 ,应当把杜绝医源性传播和乙肝免疫预防作为重点。
Objective Discussing the status on which the college students majoring cuisine infected with HBV and providing scientific grounds for constituting the countermeasure guarding against HBV.Methods To examine HBV among 264 college students majoring cuisine and the HBV infection markers of 16 HBsAg carriers among them had been reserved for 3 years.Firstly all the examinates'HBsAg were examined with RPHA.Secondly the other infection markers of the students whose HBsAg were positive were examined with ELISA.Lastly ALT was examined with King's method.Results The average positive rate of HBsAg was 6.30%.Statistically the marked difference in HBV infection rate was founded between the every grade (χ 2=12.06 P <0.005).The serum which HBsAg, HBeAg or HBsAg, anti-HBc synchronously were positive was 12.77 percent of that which HBsAg was positive.Conclusions It's significative on the management of the persons infected with HBV to have physical examination on the college students majoring cuisine termly, to develop the dynamic examination on HBsAg and the other HBV infection markers, to reinforce visitations for persons having infectivity. Furthermore, this article advises that we should emphasis on putting an end to nosocomial spread and HBV immunity.
出处
《预防医学情报杂志》
CAS
2002年第6期501-503,共3页
Journal of Preventive Medicine Information