摘要
目的 :检测肺癌患者骨髓微小转移灶 ,并探讨其临床意义。 方法 :用免疫组化法检测肺癌患者骨髓上皮膜抗原 (EMA)阳性表达细胞 ,分析其与肺癌病理类型、分期及远处转移的关系。 结果 :112例肺癌患者中 36例骨髓检出EMA阳性细胞 ,阳性率为 32 .1%。EMA阳性细胞的检出率与病期及远处转移有关 ,晚期及已发生转移的病例检出率明显增高。 结论 :骨髓EMA表达阳性细胞的检测 ,可作为评价肺癌患者病期及转移倾向的重要指标之一。
Objectives:To study the relationship among the bone marrow micrometastasis,the clinical stages and the general metastasis in lung cancers. Methods:The bone marrow epithelial membrane antigen (EMA) positive cells from patients with lung cancers were measured by immunocytochemical assay by an antibody probe. Results:EMA positive cells were detected in the bone marrows in 36 patients (32.1%), the positive rates correlated with the stages of patients, and the recurrence rate in patients with remote metastasis were higher than those without bone marrow metastasis. Conclusions: The detection of EMA positive cells is important in evaluating the stage of patients with lung cancers and also to evaluate the possibility of recurrence and genenral metastasis.
出处
《医学研究生学报》
CAS
2002年第5期434-435,T003,共3页
Journal of Medical Postgraduates
关键词
肺癌
骨髓微小转移灶
检测
临床意义
免疫组化
上皮膜抗原
Lung neoplasm
Micrometastasis of bone marrow
Immunohistochemistry
Epithelial membrane antigen
