摘要
目的 评价淋巴显像在乳腺癌前哨淋巴结活检中的价值。方法 采用肿瘤周围或皮下注射99mTc标记的硫胶体的方法 ,先行术前淋巴显像 ,术中γ探测仪引导下行前哨淋巴结活检 ,分析影响其检出率的相关因素。结果 95例患者中 ,有 88例 (92 .6 % )在术前的淋巴显像中显示淋巴引流 ,其中 39例 (44 .3% )患者有腋窝淋巴结以外的淋巴引流。术中在γ探测仪引导下成功发现前哨淋巴结的有 91例 (95 .8% )。术前淋巴显像是否清楚与前哨淋巴结检出率显著相关 (P =0 .0 2 5 )。结论淋巴显像能发现腋窝以外的前哨淋巴结 ,联合使用淋巴显像与γ探测仪行前哨淋巴结活检的方法是可行的 ,值得在临床上推广使用。
Objective To evaluate the feasibility of lymphoscintigraphy in sentinel lymph node biopsy of breast cancer. Method Lymphoscintigraphy was performed after peritumoral or subdermal injection of radioactive colloid. Then, sentinel lymph node (SLN) biopsy guided by γ detector probe was performed. Factors correlated with identification-detection rate were assessed. Results Lymphatic drainage was present in preoperative lymphoscintigraphy in 88(93%) out of 95 patients, with 39 (44.3%) positive for lymphatic drainage other than in the axilla. A total of 91 (95.8%) patients had their SLN identified in the intraoperative procedure. The quality of lymphoscintigraphic image was closely related to SLN identification-detection rate in the intraoperative procedure (P=0.025). Conclusion Sentinel lymph node outside the axilla can be detected by lymphoscintigraphy. The combination of lymphoscintigraphy and γ detector probe for sentinel lymph node biopsy of breast cancer not only is acceptable but promising.
出处
《中华肿瘤杂志》
CAS
CSCD
北大核心
2002年第6期616-618,共3页
Chinese Journal of Oncology
基金
国际抗癌联盟资金 (92 / 1999)
国家杰出自然科学基金(3 0 0 2 5 0 15 )
关键词
乳腺癌
乳腺肿瘤
淋巴显影
淋巴转移
活组织检查
Breast neoplasms/diagnosis
Lymphoscintigraphy
Lymphatic metastasis
Biopsy
