摘要
目的 探讨分化型甲状腺癌 (WDTC)侵犯喉气管的手术治疗方法。方法 回顾性分析2 1例WDTC侵犯喉气管患者的临床资料。根据手术方式的不同 ,将患者分为肿瘤根治组 (A组 ,5例 )、肿瘤剔除组 (B组 ,11例 )和姑息性切除组 (C组 ,5例 )。结果 2 1例患者的 3,5 ,7年生存率分别为 81.0 % (17 2 1)、6 1.9% (13 2 1)和 4 2 .9% (9 2 1)。A、B两组的生存率均明显高于C组 (P <0 .0 0 1,P <0 .0 3) ,A组的 5 ,7年生存率虽高于B组 ,但差异无显著性 (P >0 .0 5 )。结论 多数WDTC侵犯喉气管患者宜采取保守性手术 ,如肿瘤侵及管腔内 ,患者出现呼吸困难和呼吸道出血等并发症 ,则需要采取根治性手术。
Objective To discuss the method of surgical treatment for well-differentiated thyroid carcinoma (WDTC) invading the laryngotrachea. Methods According to surgical procedure, 21 patients with WDTC invading the laryngotrachea were divided into tumor radical removal group(Group A, n=5), tumor chisel group (Group B, n=11) and tumor debulking group (Group C, n=5). Results The overall 3-, 5- and 7-year survival rates were 81.0%(17/21), 61.9% (13/21) and 42.9% with better result in Group A (P<0.001) and Group B (P<0.03) than in Group C, however, without any significance between Groups A and B (P> 0.05). Conclusion Conservative operation should be considered in most patients with well differentiated thyroid carcinoma invading the laryngotrachea. Only in the presence of intraluminal invasion in the trachea causing hemoptysis and airway obstruction does it require radical operation.
出处
《中华肿瘤杂志》
CAS
CSCD
北大核心
2002年第6期589-591,共3页
Chinese Journal of Oncology
关键词
分化型甲状腺癌
外科治疗
喉肿瘤
WDTC
临床表现
Thyroid neoplasms/surgery
Laryngeal neoplasms/surgery
Tracheal neoplasms/surgery
