摘要
研究了单细胞红藻紫球藻 (Porphyridiumsp.)对60Coγ_射线辐射后小鼠免疫功能的影响。紫球藻胞外多糖 (PolysaccharideofPorphyridiumsp.PSP)在体内对小鼠免疫功能具正调节作用 ,具体表现为显著提高小鼠脾细胞增殖水平、自然杀伤细胞 (NaturalKillerCell,NK细胞 )杀伤活性和白细胞介素2(Interleukin2 ,IL_2)活性。IL_2可以激活T细胞 ,增强NK细胞的活性 ,改善60Coγ_射线辐射引起的免疫功能低下而对机体造成的不利影响 ,使小鼠的免疫功能达到甚至超过正常水平。
The extracellular polysaccharide from the unicellular red alga,Porphyridium sp.UTEX637,is a kind of sulfated polysaccharide.The anti_irradiation activity on the immune function of 60 Coγ_ray irradiated mice was investigated in this paper.The results suggest that the extracellular polysaccharide(PSP)could obviously enhance the spleen cells prolifera-tion and the activities of Natural Killer cells and Interleukin2.The present study may indicate that the extracellular polysaccharide of Porphyridium sp.has anti_irradiation activities.
出处
《海洋科学》
CAS
CSCD
北大核心
2002年第12期53-56,共4页
Marine Sciences
关键词
紫球藻
胞外多糖
抗辐射
生物学活性
Porphyridium sp.,Extracellular polysaccharide,Anti-irradiation,Immune
