2WANG Z,QIU S J,YE S L,et al.Combined IL-12 and GM-CSF gene therapy for murine hepatocellular carcinoma[J].Cancer Gene Ther,2001,8(10):751-758.
3WANG L H,JU D W,SUN Y,et al.The potent antitumor effects of combined p16 gene and GM-CSF gene therapy through efficient induction of antitumor immunity[J].J Cancer Res Clin Oncol,2001,127(2):101-108.
4JAFFEE E M,HRUBAN R H,BIEDRZYCKI B,et al.Novel allogeneic granulocyte-macrophage colony-stimulating factor-secreting tumor vaccine for pancreatic cancer:a phase I trial of safety and immune activation[J].J Clin Oncol,2001,19(1):145-156.
5DOU J,CHEN J S J,ZHAO F S,et al.Novel constructs of tuberculosis gene vaccine and its immune effect in mice[J].Cell Mol Immunol,2005,2(2):88-93.
6DOU J,TANG Q,ZHAO F S,et al.Comparison of immune responses induced in mice by vaccination with DNA vaccine constructs expressing mycobacterial antigen 85A & interleukin-21 and bacillus Galmette-Guérin[J].Immunol Invest,2008,37(2):113-127.
7DOU J,HONG X W,ZHAO F S,et al.Investigation of GM-CSF immune accessory effects in tumor-bearing mice by direct gene immunization[J].Immunol Invest,2006,35:227-237.
8TSANG T C,HARRIS D T,AKPORIAYE E T,et al.Mammalian expression vector with two multiple cloning sites for expression of two foreign genes[J].Biotechniques,1997,22(1):68.
9DOU J,TANG Q,YU F L,et al.Investigation of immune effect based on BCG priming and plasmid DNA expressing Ag85A & GM-CSF boosting in Balb/c mice model[J].Immunobiology,2010,215(2):133-142.
10DOU J,WANG Y,WANG J,et al.Antitumor efficacy induced by human ovarian cancer secreting IL-21 alone or combination with GM-CSF cytokines in nude mice model[J].Immunobiology,2009,214(1):483-492.
