摘要
目的观察VMAT在局部晚期宫颈癌中应用效果。方法回顾性收集135例局部晚期宫颈癌患者临床资料,根据治疗方法的不同分为两组,VMAT 70例,IMRT 65例。计划靶体积剂量50.4Gy,比较两组靶区参数、危及器官剂量、治疗时间、近期疗效、急性不良反应及OS。结果VMAT组CI值高于IMRT组(t=2.04,P=0.04),治疗时间短于IMRT组(t=30.57,P<0.01)。两组其他指标比较均无统计学意义(P>0.05)。结论与IMRT相比,VMAT的适形度更好,可以明确缩短局部晚期宫颈癌患者的治疗时间。
Objective To observe the application effect of VMAT in locally advanced cervical cancer.Methods The clinical data of 135 patients with locally advanced cervical cancer were retrospectively collected and divided into two groups according to different treatment methods:70 VMAT cases and 65 IMRT cases.The target volume dose was planned to be 50.4Gy,and the target parameters,organ dose at risk,treatment time,short-term efficacy,acute adverse reactions and Overall Survival(OS)were compared between the two groups.Results CI value in VMAT group was higher than that in IMRT group(t=2.04,P=0.04),and treatment time was shorter than that in IMRT group(t=30.57,P<0.001).There was no statistical significance in other indexes between the two groups(P>0.05).Conclusion Compared with IMRT,VMAT has better conformation and can clearly shorten the treatment time of locally advanced cervical cancer patients.
作者
刘蓓蓓
李秀敏
LIU Bei-bei;LI Xiu-min(Binzhou Medical University,Yantai,China 264003;Linyi Cancer Hospital,Linyi,China 276000)
出处
《山东医学高等专科学校学报》
2024年第6期7-10,共4页
Journal of Shandong Medical College
基金
临沂市科技发展计划项目(No.202020059)。
关键词
宫颈癌
容积旋转调强放疗
生存率
不良反应
靶区参数
Cervical cancer
Volume rotation intensity modulated radiotherapy
Survival rate
Adverse reactions
Target parameter
