摘要
目的探讨高弹海绵填塞离心杯离心对提高一次成浆率的效果。方法随机抽取南通市中心血站2022年8—12月采集的保存于2~6℃当天制备的无偿献血者血液,在滤除白细胞后血袋配平,实验组装入离心杯后用高弹海绵填塞后离心,对照组未使用高弹海绵填塞离心。比较两组一次成浆率及离心破损的差异。结果实验组一次成浆率为98.33%,明显高于对照组的90.53%,差异有统计学意义(χ^(2)=105.800,P<0.05)。实验组300 ml和400 ml血液一次成浆率分别为98.07%和98.56%,均较对照组有明显提高,差异有统计学意义(χ^(2)=59.316,P<0.05;χ^(2)=34.388,P<0.05)。两组离心破损渗漏率比较,差异无统计学意义(χ^(2)=2.409,P>0.05)。结论应用高弹海绵填塞离心杯离心,可有效改善血袋离心过程中出现的折皱、塌陷、红细胞贴壁等问题,明显提高血液一次成浆率。
Objective To explore the effect of filling centrifugal cup with high-elastic sponge on improving the primary slurry rate.Methods The blood of voluntary blood donors collected from Blood Center of Nantong from August to December 2022 and stored at 2-6℃was randomly selected,and the blood bags were balanced after leucocytes were filtered.After the experiment was assembled into a centrifuge cup,it was filled with high-elastic sponge and centrifuged.The control group did not use high-elastic sponge to fill and centrifuge.The differences of primary slurry rate and centrifugal damage between the two groups were compared.Results The primary slurry rate in the experimental group was 98.33%,which was significantly higher than that in the control group(90.53%),and the difference was statistically significant(χ^(2)=105.800,P<0.05).The primary slurry rate of 300 ml and 400 ml blood in the experimental group were 98.07%and 98.56%,respectively,which were significantly higher than those in the control group(χ^(2)=59.316,P<0.05.χ^(2)=34.388,P<0.05).There was no significant difference in the centrifugal breakage leakage rate between the two groups(χ^(2)=2.409,P>0.05).Conclusion Using filling centrifugal cup with high-elastic sponge for centrifugation can effectively improve the problems such as wrinkling,collapse and red blood cells adhesion during the centrifugation of blood bags,obviously improve the primary slurry rate of blood.
作者
王小芹
王欣若
汤蓉蓉
WANG Xiaoqin;WANG Xinruo;TANG Rongrong(Blood Center of Nantong,Jiangsu,Nantong 226007,China;School of Life Science,Nantong University,Jiangsu,Nantong 226019,China)
出处
《中国医药科学》
2024年第23期173-176,共4页
China Medicine And Pharmacy
基金
江苏省南通市卫生健康委员会科研课题(MS2022097)。
关键词
高弹海绵
填塞离心
一次成浆率
血液制备
High-elastic sponge
Filling centrifugation
Primary slurry rate
Blood preparation
