摘要
Objective:To investigate the changes of mRNA expression level of zinc finger and SCAN domain containing 12(ZSCAN12)in peripheral blood of first-ep-isode schizophrenia(SCZ).Methods:For our study we selected 17 individuals who had a first episode of SCZ and were hospitalized in the Affiliated Mental Hospital of Kunming Medical University from January 2024 to June 2024;we measured the mRNA expression level of ZSCAN12 in peripheral lymphocytes by quantitative re-al-time polymerase chain reaction(Q-PCR)method in the study group and compared it to a control group consisting of 15 healthy patients.Results:There was no significant difference in the expression of ZSCAN12 mRNA in pe-ripheral blood lymphocytes of SCZ patients and healthy controls(P>0.05).Conclusion:The expression of ZS-CAN12 mRNA was not significantly abnormal in SCZ patients in this study.
基金
supported by Research Project of Yunnan Provincial Psychiatric Hospital(SJKY-2023-08).
