摘要
目的探讨右美托咪定预处理复合腹横肌平面阻滞麻醉对腹腔镜下结直肠癌根治术患者麻醉效果及认知功能的影响。方法选取2021年10月至2022年10月我院收治的120例行腹腔镜下结直肠癌根治术患者,通过随机数字表法将其分为对照组和观察组,各60例。对照组采用腹横肌平面阻滞麻醉,观察组采用右美托咪定预处理+腹横肌平面阻滞麻醉。比较两组的麻醉效果。结果观察组的感觉阻滞和运动阻滞的起效时间、达到最高平面时间短于对照组,持续时间长于对照组(P<0.05)。手术10 min(T_(1))、术毕(T_(2)),观察组的平均动脉压(MAP)、血氧饱和度(SPO2)高于对照组(P<0.05)。术后12、24 h,观察组的简易精神状态评估量表(MMSE)、蒙特利尔认知评估量表(Mo CA)评分高于对照组(P<0.05)。结论右美托咪定预处理复合腹横肌平面阻滞麻醉能提高腹腔镜下结直肠癌根治术患者的麻醉效果,维持血流动力学稳定,减轻对术后认知功能的影响。
Objective To investigate the influences of dexmedetomidine pretreatment combined with transversus abdominis plane block anesthesia on anesthesia effect and cognitive function in patients undergoing laparoscopic radical resection of colorectal cancer.Methods A total of 120 patients undergoing laparoscopic radical resection of colorectal cancer in our hospital from October 2021 to October 2022 were selected and divided into control group and observation group by random number table method,with 60 cases in each group.The control group was treated with transversus abdominis plane block anesthesia,and the observation group was treated with dexmedetomidine pretreatment+transversus abdominis plane block anesthesia.The anesthetic effects of the two groups were compared.Results The onset time and the time to reach the highest plane of sensory block and motor block in the observation group were shorter than those in the control group,and the duration was longer than that in the control group(P<0.05).At 10 min of operation(T_(1))and the end of operation(T_(2)),the mean arterial pressure(MAP)and blood oxygen saturation(SpO2)in the observation group were higher than those in the control group(P<0.05).At 12 and 24 h after operation,the scores of Mini-Mental State Examination(MMSE)and Montreal Cognitive Assessment Scale(MoCA)in the observation group were higher than those in the control group(P<0.05).Conclusion Dexmedetomidine pretreatment combined with transversus abdominis plane block anesthesia can improve the anesthetic effect of patients undergoing laparoscopic radical resection of colorectal cancer,maintain hemodynamic stability,and reduce the impact on postoperative cognitive function.
作者
赵晓龙
霍鹏伟
张成江
赵锦阳
ZHAO Xiaolong;HUO Pengwei;ZHANG Chengjiang;ZHAO Jinyang(Yulin Hospital,the First Affiliated Hospital of Xi'an Jiaotong University,Yulin 719000,China)
出处
《临床医学研究与实践》
2024年第26期102-105,共4页
Clinical Research and Practice
关键词
右美托咪定
腹横肌平面阻滞
结直肠癌根治术
demetomidine
transversus abdominis plane block anesthesia
radical resection of colorectal cancer
