摘要
目的分析补阳还五汤联合胞磷胆碱治疗气虚血瘀型脑梗死恢复期患者的临床疗效。方法90例气虚血瘀型脑梗死恢复期患者,随机分为A组与B组,每组45例。A组使用胞磷胆碱钠胶囊治疗,B组使用补阳还五汤+胞磷胆碱钠胶囊治疗。比较两组患者的临床疗效、不良反应发生情况及治疗前后功能评分[美国国立卫生研究院卒中量表(NIHSS)评分、生活质量量表(QOL)评分和Barthel指数]。结果B组患者治疗总有效率为95.6%,高于A组的66.7%,组间对比有统计学差异(P<0.05)。A组患者不良反应发生率为4.4%(2/45),与B组的6.7%(3/45)对比无统计学差异(P>0.05)。治疗后,两组患者NIHSS评分显著降低,QOL评分和Barthel指数明显升高,且B组NIHSS评分(5.6±2.7)分低于A组的(8.7±2.2)分,QOL评分(77.7±11.2)分、Barthel指数(59.5±10.2)分均高于A组的(57.5±10.0)、(39.7±7.9)分,组间对比有统计学差异(P<0.05)。结论补阳还五汤与胞磷胆碱联合治疗气虚血瘀型脑梗死恢复期效果良好,值得推广。
Objective To analyze the clinical efficacy of Buyang Huanwu Tang combined with citicoline in the treatment of Qi deficiency and blood stasis type cerebral infarction.Methods 90 patients with Qi deficiency and blood stasis type cerebral infarction were randomly divided into group A and group B,each with 45 cases.Group A was treated with citicoline sodium capsules,while group B was treated with Buyang Huanwu Tang+citicoline sodium capsules.Patients in both groups were compared in terms of clinical efficacy,occurrence of adverse reactions and functional scores[National Institutes of Health Stroke Scale(NIHSS)score,Quality of Life Scale(QOL)score and Barthel index]before and after treatment.Results The total effective rate of group B was 95.6%,which was higher than 66.7%of group A,and the difference between groups was statistically significant(P<0.05).The incidence of adverse reactions in group A was 4.4%(2/45),which had no significant difference compared with 6.7%(3/45)in group B(P>0.05).After treatment,NIHSS score decreased significantly,QOL score and Barthel index increased significantly in both groups;group B had lower NIHSS score of(5.6±2.7)points than(8.7±2.2)points in group A;group B had QOL score of(77.7±11.2)points and Barthel index of(59.5±10.2)points,which were higher than(57.5±10.0)and(39.7±7.9)points in group A;the difference between groups was statistically significant(P<0.05).Conclusion The combination of Buyang Huanwu Tang and citicoline has a good effect on the recovery period of Qi deficiency and blood stasis type cerebral infarction,and is worth promoting.
作者
徐晖
林燕
何渊
石一杰
XU Hui;LIN Yan;HE Yuan(Traditional Chinese Medicine Hospital of Zengcheng District,Guangzhou 511399,China)
出处
《中国实用医药》
2024年第14期144-147,共4页
China Practical Medicine
关键词
气虚血瘀型脑梗死
补阳还五汤
不良反应
胞磷胆碱
Qi deficiency and blood stasis type cerebral infarction
Buyang Huanwu Tang
Adverse reactions
Citicoline
