摘要
IgA血管炎(IgAV)是一种由IgA沉积在小血管引起的自身免疫性疾病,除了非血小板减少性紫癜表现,还有胃肠道、关节及肾脏受累。该病具有自限性,少数累及肾脏者,可在晚年发展为终末期肾脏疾病。文章对儿童IgAV临床特征及累及肾脏的相关机制进行综述,并探讨该病的治疗及预后。
IgA vasculitis(IgAV)is an autoimmune disease caused by IgA deposition in small blood vessels.It is characterized by non-thrombocytopenic purpura,abdominal pain,joint swelling and pain,hematuria or proteinuria.The disease is self-limited,with only a minority progressing to end-stage renal disease in later life.This paper reviews the clinical features of IgAV in children and the mechanisms of renal involvement,and discusses the treatment and prognosis of the disease.
作者
柴亚惠(综述)
杨达胜(综述)
张贺(综述)
毕凌云(审校)
CHAI Yahui;YANG Dasheng;ZHANG He;BI Lingyun(The First Affiliated Hospital of Xinxiang Medical University,Weihui 453100,Heinan,China)
出处
《临床儿科杂志》
CAS
CSCD
北大核心
2024年第8期737-740,746,共5页
Journal of Clinical Pediatrics
