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女性不孕症在行体外受精-胚胎移植前结核感染筛查及诊疗进展

Progress in tuberculosis infection screening,diagnosis and treatment of female infertility patients before in vitro fertilization-embryo transfer
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摘要 女性生殖系统结核是女性不孕的常见因素,体外受精-胚胎移植(in vitro fertilization-embryo transfer,IVF-ET)是治疗女性不孕症的有效方法,女性生殖系统结核患者在进行IVE-ET过程中存在诱发结核活动和复发的风险,从而导致该部分人群IVF-ET成功率低,不良事件发生率高。中国结核病患者及结核分枝杆菌潜伏感染者基数大,不孕症女性进行IVF-ET前的结核感染筛查,以及采取必要的干预措施可以提高IVF-ET成功率,降低不良事件发生率。目前,国内外针对女性生殖系统结核感染的不孕症女性行IVE-ET前的规范处置尚无定论,笔者通过介绍实验室检查、影像学检查、内镜检查、病理组织检查、抗结核治疗在不孕症女性生殖系统结核感染的筛查、诊断、治疗过程中的应用进行综述,为不孕症女性在IVF-ET前的结核感染筛查及诊疗提供临床参考。 In vitro fertilization-embryo transfer(IVF-ET)is an effective method for treating female infertility.During IVE-ET course,patients with female reproductive system tuberculosis have certain risk of activating tuberculosis to recurrent,which leads to low success rate of IVF-ET and high incidence of adverse events.In China,large number of patients have active tuberculosis disease or tuberculosis latent infection.Screening for tuberculosis infection before IVF-ET in infertile women and then taking necessary intervention can improve the success rate of IVF-ET and reduce the incidence of adverse events.At present,there is no conclusion on standard treatment before IVE-ET for infertile women with female reproductive system tuberculosis infection.This article reviews the application of laboratory,imaging,endoscopic,and pathological examination and anti-tuberculosis treatment in screening,diagnosis and treatment of female reproductive system tuberculosis infection,in order to provide clinical reference for the screening and treatment of tuberculosis infection in infertile women before IVF-ET.
作者 李亚波 樊丽娟 孙秀利 缑良芝 任倍莹 师娟子 王芳 马晓玲 谢永宏 刘鑫 仵倩红 Li Yabo;Fan Lijuan;Sun Xiuli;Gou Liangzhi;Ren Beiying;Shi Juanzi;Wang Fang;Ma Xiaoling;Xie Yonghong;Liu Xin;Wu Qianhong(Department of Gynecology,Shaanxi Provincial Tuberculosis Prevention and Control Hospital,Xi’an 710100,China;Department of Reproduction,Northwest Women and Children’s Hospital,Xi’an 710061,China;Reproductive Center,the Second Affiliated Hospital of Lanzhou University,Lanzhou 730030,China;Reproductive Center,the First Affiliated Hospital of Lanzhou University,Lanzhou 730000,China;Department of Respiratory Medicine,Air Force Medical University,Xi’an 710032,China;Department of Geriatrics,the Second People’s Hospital of Shaanxi Province(Shaanxi Province Geriatric Hospital),Xi’an 710005,China)
出处 《结核与肺部疾病杂志》 2024年第4期352-357,共6页 Journal of Tuberculosis and Lung Disease
基金 西安市科学技术局西安市财政局基金(22YXYJ0160)。
关键词 结核 受精 体外 胚胎移植 诊断 治疗学 Tuberculosis Fertilization in vitro Embryo transfer Diagnosis Therapeutics
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