摘要
目的 探讨子宫内膜癌(EC)患者远期预后的影响因素。方法 选取自2016年1月至2018年6月收治的176例子宫内膜癌患者为研究对象,根据术后5年预后情况分为预后良好组(n=148)和预后不良组(n=28),对两组可能与预后相关的因素,包括病理类型、病理分期、淋巴结转移等因素进行单因素分析。应用Logistic回归分析EC远期预后的影响因素。结果 预后不良组年龄≥60岁、绝经、肌层浸润深度≥1/2、非雌激素依赖型、病理分期Ⅲ期、有淋巴结转移患者的构成比例均高于预后良好组,差异有统计学意义(P<0.05)。Logistic回归分析结果显示,肌层浸润深度≥1/2、非雌激素依赖型、病理分期Ⅲ期是EC患者远期预后的影响因素(P<0.05)。结论 肌层浸润深、非雌激素依赖型、病理分期Ⅲ期是EC患者远期预后的影响因素。
Objective To analyze the factors related to the long-term prognosis of patients with endometrial cancer(EC).Method A retrospective analysis was conducted to select 176 patients with endometrial cancer in our hospital from January 2016 to June 2018 as the study objects.The patients were divided into two groups based on the prognosis 5 years after surgery.They were divided into the good prognosis group(n=148)and the poor prognosis group(n=28).Univariate analysis was performed on factors including,pathological type,pathological stage,lymph node metastasis.Factors with statistical significance were included in Logistic regression analysis.Results The proportion of patients in the poor prognosis group with age≥60 years old,menopause,depth of muscle invasion≥1/2,non-estrogen-dependent,pathological stageⅢand lymph node metastasis was higher than that in the good prognosis group,with statistical significance(P<0.05).Logistic regression analysis showed that myographic infiltration depth≥1/2,non-estrogen-dependent,and pathological stage III were the factors affecting the long-term prognosis of EC patients(P<0.05).Conclusion Deep infiltration of muscle layer,non-estrogen-dependent type and pathological stageⅢare the factors influencing the long term prognosis of EC patients.
作者
蒋艺莎
裴丽鹏
李广莹
曲长红
徐斌
JIANG Yi-sha;PEI Li-peng;LI Guang-ying;QU Chang-hong;XU Bin(Department of Obstetrics and Gynecology,General Hospital of Northern Theater Command,Shenyang 110016,China)
出处
《创伤与急危重病医学》
2024年第1期47-49,54,共4页
Trauma and Critical Care Medicine
基金
辽宁省科学技术计划项目(2022JH2/101500019)。
关键词
子宫内膜癌
远期预后
病理因素
Endometrial cancer
Long term prognosis
Pathological factors
