摘要
多参数磁共振(multiple parameter MRI,mpMRI)是目前前列腺癌无创性检出、定位和分期的首选影像学方法。然而,mpMRI图像解读基于阅片者的经验和主观判断,往往会造成诊断偏差。MRI定量技术能够对前列腺病灶的病理生理学特性进行更加客观、精准地分析,传统的定量技术包括扩散张量成像、扩散峰度成像、体内非相干运动成像及T2 mapping等,但它们各自的局限性使之不能广泛应用于临床。合成磁共振序列是一种新型定量扫描方法,单次扫描后可获得多组基于组织病理生理特性的绝对测量值,具有高效率和高容错率,在前列腺癌的诊断中有良好的临床前景。本文对传统及新型MRI定量扫描方法在前列腺癌中的临床应用展开综述。
Currently,multiple parameter MRI(mpMRI)is the preferred imaging modality for the non-invasive detection,localization,and staging of prostate cancer.However,the interpretation of mpMRI images relies on the experience and subjective judgment of the reader,leading to potential diagnostic bias.Quantitative MRI techniques can provide a more objective and precise interpretation for the pathophysiological characteristics of prostate lesions.Traditional quantitative techniques include DTI,DKI,IVIM and T2 mapping,but their limitations restrict their widespread clinical utility.Nevertheless,synthetic MRI has emerged as a novel quantitative technique that enables the acquisition of multiple sets of absolute measurements based on histopathophysiological properties in a single scan.With its high scanning efficiency and error tolerance rate,synthetic MRI holds promising clinical prospects in prostate cancer.This review discusses the clinical applications of both traditional and novel quantitative MRI techniques in prostate cancer.
作者
高钟秀
顾莹莹
唐立钧
GAO Zhongxiu;GU Yingying;TANG Lijun(Department of Nuclear Medcine,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China)
出处
《南京医科大学学报（自然科学版）》
CAS
北大核心
2024年第7期1025-1030,共6页
Journal of Nanjing Medical University(Natural Sciences)
基金
江苏省医学重点人才基金项目(ZDRCB2016003)。
