摘要
目的:探究糖康1号对2型糖尿病患者的影响。方法:选取2020年12月—2021年12月合肥市播州区中医院内分泌科住院部收治的2型糖尿病患者60例为研究对象,根据随机抽签方法分为观察组和对照组,各30例。对照组采用常规胰岛素治疗,观察组采用胰岛素联合糖康1号治疗。比较两组血糖[空腹血糖(FBG)、餐后2h血糖(2hPBG)、糖化血红蛋白(HbA1c)]、中医证候积分、治疗效果及β细胞功能指数(HOMA-β)、胰岛素抵抗指数(HOMA-IR)。结果:治疗前,两组FBG、2 hPBG、HbA1c水平及中医证候积分比较,差异无统计学意义(P>0.05);治疗后,两组FBG、2 hPBG、HbA1c水平及中医证候积分低于治疗前,观察组低于对照组,差异有统计学意义(P<0.05)。观察组治疗总有效率高于对照组,差异有统计学意义(P=0.020)。治疗前,两组HOMA-β、HOMA-IR水平比较,差异无统计学意义(P>0.05);治疗后,两组HOMA-β水平高于治疗前,HOMA-IR水平低于治疗前,观察组HOMA-β高于对照组,HOMA-IR水平低于对照组,差异有统计学意义(P<0.05)。结论:胰岛素联合糖康1号治疗2型糖尿病效果较好,可降低患者血糖水平,减轻临床症状,改善胰岛β细胞功能。
Objective:To explore the effect of Tangkang 1 on patients with type 2 diabetes.Methods:Sixty patients with type 2 diabetes admitted to the Inpatient Department of Endocrinology of Zunyi Bozhou District Hospital of Traditional Chinese Medicine from December 2020 to December 2021 were selected as the study objects,and were divided into observation group and control group according to random drawing method,with thirty cases in each group.The control group was treated with conventional insulin,and the observation group was treated with insulin combined with Tangkang 1.Blood glucose[fasting blood glucose(FBG),2 h postprandial blood glucose(2 hPBG),glycated hemoglobin(HbA1c)],traditional Chinese medicine syndrome score,therapeutic effect,βcell function index(HOMA-β)and insulin resistance index(HOMA-IR)of the two groups were compared.Results:Before treatment,there were no significant differences in FBG,2 hPBG,HbA1c levels and traditional Chinese medicine syndrome scores between the two groups(P>0.05);after treatment,the levels of FBG,2 hPBG,HbA1c and traditional Chinese medicine syndrome scores of the two groups were lower than before treatment,and the observation group was lower than the control group,the difference was statistically significant(P<0.05).The total effective rate of the observation group was higher than that of the control group,the difference was statistically significant(P=0.020).Before treatment,there was no significant difference in HOMA-βand HOMA-IR levels between the two groups(P>0.05);after treatment,HOMA-βlevel in the two groups was higher than before treatment,HOMA-IR level was lower than before treatment,HOMA-βlevel in the observation group was higher than control group,HOMA-IR level was lower than control group,the difference was statistically significant(P<0.05).Conclusion:Insulin combined with Tangkang 1 is effective in the treatment of type 2 diabetes,which can reduce the blood glucose level,alleviate clinical symptoms and improve the function of islet beta cells.
作者
苟世亮
裴家竹
陈光辉
Gou Shiliang;Pei Jiazhu;Chen Guanghui(Zunyi Bozhou District Hospital of Traditional Chinese Medicine,Zunyi 563100,Guizhou Province,China)
出处
《中外医药研究》
2024年第15期108-110,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
关键词
糖康1号
2型糖尿病
血糖
胰岛素
Tangkang 1
Type 2 diabetes
Blood glucose
Insulin
