摘要
通过模仿天然细胞外基质的成分和结构特性对材料表面形貌进行设计与调控,可获得新型仿生材料,并广泛应用于生物医学领域。其中,静电纺纳米纤维通过调控孔隙率、比表面积及微纳米结构等,可以模拟天然细胞外基质的结构,实现其生物功能。本文将提供不同表面形貌电纺纤维的概述。首先介绍静电纺丝的原理、设备和参数,然后讨论电纺纤维的4种表面形貌:纳米孔、串晶、沟槽和皱缩结构的制备原理、方法及在生物医学领域的应用,并对该领域相关研究和研究现状进行评价。
By emulating the composition and structural features of the natural extracellular matrix,the design and regulation of material surface morphologies can yield novel biomimetic materials that find extensive applications in the field of biomedical science.Among these,electrospun nanofibers,by manipulating parameters like porosity,surface area,and micro/nanoarchitecture,can replicate the structure of the native extracellular matrix,thus achieving corresponding biological functionalities.This article offers an overview of various surface morphologies of electrospun fibers.It begins by outlining the principles,equipment,and parameters of electrospinning,and subsequently delves into the preparation principles and methods of four types of surface morphologies of electro-spun fibers:Nanopores,crystal arrays,grooves,and wrinkled structures.It explores their applications in the bio-medical field,evaluates pertinent research,and provides an up-to-date assessment of the most relevant studies in this domain.
作者
文美玲
高翔
刘阳
安美文
WEN Meiling;GAO Xiang;LIU Yang;AN Meiwen(Shanxi Key Laboratory of Material Strength&Structural Impact,Institute of Biomedical Engineering,College of Biomedical Engineering,Taiyuan University of Technology,Taiyuan 030024,China;Research Center for Nanobiomaterials&Regenerative Medicine,College of Biomedical Engineering,Taiyuan University of Technology,Taiyuan 030024,China)
出处
《复合材料学报》
EI
CAS
CSCD
北大核心
2024年第5期2236-2248,共13页
Acta Materiae Compositae Sinica
基金
国家自然科学基金(12272251
12002232)
山西省基础研究计划-青年科学研究项目(202103021223100)。
关键词
静电纺丝
纤维
材料表面形貌
生物医学应用
组织工程
electrospun
fiber
material surface morphology
biomedical applications
tissue engineering
