摘要
目的探讨糖脂代谢与子宫内膜癌的相关性。方法选取2017年1月-2022年12月收治于内蒙古自治区包头市第四医院妇科的50例子宫内膜不典型增生、50例子宫内膜癌患者为病例组,选取同期子宫内膜单纯性增生或息肉样增生患者100例作为对照组。对研究对象进行各项糖脂代谢指标的检测。结果病例组患者年龄(63.45±4.35)岁、空腹血糖(6.99±2.41)mmol/L、三酰甘油(3.85±0.24)mmol/L、低密度脂蛋白(4.25±0.38)mmol/L、高密度脂蛋白(1.52±0.47)mmol/L、尿酸(282.56±85.62)μmol/L、身体质量指数(body mass index,BMI)(24.56±1.55)kg/m^(2)及胆固醇(4.98±0.17)mmol/L均高于对照组,差异有统计学意义(P<0.05)。结论血糖、三酰甘油、低密度脂蛋白、高密度脂蛋白、尿酸等代谢指标与子宫内膜癌的发生和发展有一定的相关性,对于存在相关风险的人群,应关注并控制这些代谢指标,以降低子宫内膜癌的发病风险,保持健康的糖脂代谢对预防子宫内膜癌的发生具有重要意义。
Objective To investigate the correlation between glycolipid metabolism and endometrial carcinoma.Methods A total of 50 cases of endometrial dysplasia and 50 cases of endometrial cancer admitted to the department of gynecology,the Fourth Hospital of Baotou,Inner Mongolia Autonomous Region from January to December 2017 were selected as the case group,and 100 cases of endometrial simple hyperplasia or polypoid hyperplasia were selected as the control group.The indexes of glucose and lipid metabolism were detected.Results The age of patients in the case group(63.45±4.35)years old,fasting blood glucose(6.99±2.41)mmol/L,triglycerides(3.85±0.24)mmol/L,low-density lipoprotein(4.25±0.38)mmol/L,high-density lipoprotein(1.52±0.47)mmol/L,uric acid(282.56±85.62)μmol/L,body mass index(BMI)(24.56±1.55)kg/m^(2),and cholesterol(4.98±0.17)mmol/L were all higher than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Blood glucose,triglyceride,low density lipoprotein,high density lipoprotein,uric acid and other metabolic indicators have a certain correlation with the occurrence and development of endometrial cancer.For people with related risks,attention should be paid to and control of these metabolic indicators to reduce the risk of endometrial cancer.Maintaining healthy glucose and lipid metabolism is of great significance for preventing the occurrence of endometrial cancer.
作者
于雷
李波
YU Lei;LI Bo(Department of Gynecology,the Fourth Hospital of Baotou,Inner Mongolia Autonomous Region,Baotou Inner Mongolia 014030,China)
出处
《中国卫生标准管理》
2024年第11期26-29,共4页
China Health Standard Management
基金
包头市卫生健康科技计划项目(wsjkkj060)
关键词
子宫内膜癌
糖脂代谢
三酰甘油
脂蛋白
血糖
相关性
endometrial cancer
glycolipid metabolism
triglycerides
lipoprotein
blood sugar
correlation
