摘要
强迫症(obsessive-compulsive disorder,OCD)是一种以强迫思维、强迫行为为主要临床表现的常见精神疾病。近年来,许多基于功能磁共振成像的影像学研究关注到强迫症状与大尺度脑网络之间的关联,现就OCD病理生理过程中涉及的默认网络、突显网络及额顶网络的功能异常,结合三网络模型假说,对强迫症状所对应的脑网络机制研究现状进行综述,以期为OCD的早期识别及干预提供新线索。
Obsessive-compulsive disorder(OCD)is a common mental disorder with obsessions and compulsions as its main clinical manifestations.In recent years,many researches using functional magnetic resonance imaging have concentrated on the relationship between obsessive-compulsive symptoms and large-scale brain networks.Combined with the triple network model hypothesis,this article reviews the current research status of brain network mechanisms corresponding to obsessive-compulsive symptoms by focusing on functional abnormalities of Default Network,Salience Network and Frontoparietal Network involved in the pathophysiological process of OCD,with a view to providing new clues for the early recognition and intervention of OCD.
作者
刘想
龙镜亦
李毅
LIU Xiang;LONG Jingyi;LI Yi(Institute of Education,China University of Geosciences,Wuhan,430074,China;Research Center for Psychological and Health Sciences,China University of Geosciences,Wuhan 430074,China;Department of Radiology,Wuhan Mental Health Center,Wuhan 430012,China;Department of Psychiatry,Wuhan Mental Health Center,Wuhan 430012,China;Department of Radiology,Wuhan Hospital for Psychotherapy,Wuhan 430012,China;Department of Psychiatry,Wuhan Hospital for Psychotherapy,Wuhan 430012,China)
出处
《神经损伤与功能重建》
2024年第6期358-361,共4页
Neural Injury and Functional Reconstruction
关键词
强迫症
功能性磁共振成像
脑网络
三网络模型
obsessive compulsive disorder
functional magnetic resonance imaging
brain network
triple network model
