摘要
低T3综合征(LT3S)是指与危重症相关的甲状腺激素代谢异常,LT3S无明显的甲状腺功能减退症状,与重度烧伤等多种危重症关系密切。在危重症的发生发展中,许多因素通过影响甲状腺激素分泌、转运及代谢诱发LT3S。LT3S是危重症发展及并发症发生的危险因素,是评估病情严重程度及预后的良好指标。该文对LT3S发病机制、与危重症的关系及治疗进展进行综述。
Low triiodothyronine syndrome(LT3S)refers to the abnormal metabolism of thyroid hormones associated with critical illness,but without obvious symptoms of hypothyroidism.LT3S is closely associated with many critical diseases,such as severe burns,etc.During the occurrence and development of critical illness,many factors can induce LT3S by affecting the secretion,transfer and metabolism of thyroid hormones.LT3S is a risk factor for the development of critical illness and the occurrence of complications.It is a good indicator for evaluating the severity and prognosis of critical diseases.In this article,the pathogenesis,relationship with critical illness and treatment progress of LT3S were reviewed.
作者
梁永鑫
汤文彬
陈宾
刘昌玲
张志
Liang Yongxin;Tang Wenbin;Chen Bin;Liu Changling;Zhang Zhi(Department of Burn and Plastic Surgery,Guangzhou Red Cross Hospital Affiliated to Jinan University,Guangzhou 510220,China)
出处
《新医学》
CAS
2024年第3期188-192,共5页
Journal of New Medicine
基金
广东省自然科学基金(2016A030313425)
广州市科技局项目(2023A03J0523)。
关键词
低T3综合征
危重症
脓毒症
重度烧伤
Low triiodothyronine syndrome
Critical illness
Sepsis
Severe burn
