摘要
药物性食管炎(DIE)是药物引发的食管黏膜损伤,患者通常以剧烈的胸骨后疼痛为首发症状而就诊,需与心脏类疾病相鉴别,且其他症状与反流性食管炎相似,临床确诊率并不高。但DIE可能引发严重的并发症,如食管狭窄、穿孔甚至纵隔脓肿和食管胸膜瘘,若处理不及时,可能造成严重后果。此外,引发食管炎的疾病(食管克罗恩病、食管白塞病、反流性食管炎、嗜酸粒细胞性食管炎、感染性食管炎、食管癌等)可能对DIE的诊断造成干扰,因此有必要加强临床医师对食管疾病的认识,以提高DIE的检出率。
Drug-induced esophagitis(DIE)is a drug-induced damage to the esophageal mucosa.The patients usually seek medical attention with severe retrosternal pain as the initial symptom,which needs to be distinguished from cardiovascular diseases.Other symptoms are similar to reflux esophagitis,and the clinical diagnosis rate is not high.But DIE may cause serious complications,such as esophageal stenosis,perforation,and even mediastinal abscess and esophageal pleural fistula,which may lead to serious consequences if not treated timely.In addition,diseases that cause esophagitis(such as Crohn′s disease,Behcet′s disease,reflux esophagitis,eosinophilic esophagitis,infectious esophagitis,esophageal cancer,etc.)may interfere with the diagnosis of DIE.Therefore,it is necessary to strengthen the understanding of esophageal diseases of the clinical physicians to improve the detection rate of DIE.
作者
孔冰慧
杨丽
白龙洲
KONG Binghui;YANG Li;BAI Longzhou(The Fifth Clinical Medical College,Henan University of Chinese Medicine,Zhengzhou 450046,China;Department of Gastroenterology,People′s Hospital of Henan University of Chinese Medicine,Zhengzhou 450053,China)
出处
《医学综述》
CAS
2024年第5期569-575,共7页
Medical Recapitulate
基金
河南省医学科技攻关计划项目(2018020818)。
关键词
药物性食管炎
内镜
食管溃疡
鉴别诊断
Drug-induced esophagitis
Endoscopy
Esophageal ulcer
Differential diagnosis
