摘要
The successful establishment of the clustered regularly interspaced short palindromic repeats(CRISPR)/CRISPR-associated protein 9(Cas9)-based genome editing in living eukaryotic cells has encouraged scientists to screen additional CRISPR/Cas systems to expand genome editing scopes[1].
作者
杨力
陈佳
Li Yang;Jia Chen(Center for Molecular Medicine,Children’s Hospital,Fudan University and Shanghai Key Laboratory of Medical Epigenetics,International Laboratory of Medical Epigenetics and Metabolism,Ministry of Science and Technology,Institutes of Biomedical Sciences,Fudan University,Shanghai 200032,China;Gene Editing Center,School of Life Science and Technology,ShanghaiTech University,Shanghai 201210,China;Shanghai Clinical Research and Trial Center,Shanghai 201210,China)
基金
supported by the Ministry of Science and Technology of China(2018YFA0801401 and 2019YFA0802804)
the National Natural Science Foundation of China(31925011 and 32371514)
the Ministry of Agriculture and Rural Affairs of China(NK2022010207)
the Shanghai Municipal Science and Technology Commission(21JC1404600)
the Program of Shanghai Academic/Technology Research Leader(23XD1422500)
the Shanghai Municipal Education Commission(SMEC)grant to the Shanghai Frontiers Science Center for Biomacromolecules and Precision Medicine at the ShanghaiTech University。