摘要
目的对外阴汗管瘤进行临床病理分析,并总结诊断及鉴别诊断的方法,以提高临床及病理医生对其认识。方法回顾性分析2例外阴汗管瘤患者临床表现、病理特征,并进行文献复习。结果2例外阴汗管瘤患者,均被临床误诊为其他疾病而进行活检。病理典型镜下表现为具有两层上皮细胞排列为条索、小团块,或者小腺样结构,伴有小的“拖尾”表现,形似蝌蚪或球拍状,这是最具有特征的组织学表现。免疫组织化学染色癌胚抗原(CEA)、上皮膜抗原(EMA)、细胞角蛋白7(CK7),SOX10、S-100、Ki-67等一组指标,有助于对其的诊断及鉴别诊断。结论外阴汗管瘤是一种少见的良性皮肤附属器肿瘤,掌握其形态学及免疫组化特征可以减少误诊、漏诊。
Objective To improve the knowledge of clinicians and pathologists on vulvar syringoma,through make clinicopathological analysis and summarize the methods of diagnosis and differential diagnosis.Methods The clinical and pathological features of 2 patients with vulvar syringoma were retrospectively analyzed,and the literature was reviewed.Results Two patients with vulvar syringoma were misdiagnosed as other diseases and underwent biopsy.Under microscope the typical pathological characteristic are two layers of epithelial cells arranged as cords,small masses,or small glandular structures,accompanied by small"tail"manifestations,like tadpoles or rackets,which is the most characteristic histological manifestation.Immunohistochemical of carcinoembryonic antigen(CEA),epithelial membrane antigen(EMA),cytokeratin 7(CK7),SOX10,S-100 and Ki-67 is helpful for its diagnosis and differential diagnosis.Conclusion Vulvar syringoma is a rare benign tumor of skin adnexal.Knew well its morphological and immunohistochemical features can reduce misdiagnosis and missed diagnosis.
作者
杨敬
赵帅华
郭梅
YANG Jing;ZHAO Shuai-hua;GUO Mei(Department of Pathology,Puyang City Anyang District Hospital,Anyang 455000,Henan Province,China;Department of Pathology,Anyang Tumor Hospital,Anyang 455000,Henan Province,China)
出处
《罕少疾病杂志》
2024年第2期87-88,共2页
Journal of Rare and Uncommon Diseases
关键词
外阴汗管瘤
诊断
鉴别诊断
免疫组织化学
Vulvar Syringoma
Diagnosis
Differential Diagnosis
Immunohistochemistry
