摘要
目的:描述和分析精神分裂症、抑郁症、双相障碍患者的自杀风险。方法:选取符合精神障碍诊断与统计手册第5版诊断标准,来自住院、门诊或社区的精神分裂症患者2016例、抑郁症患者903例和双相障碍患者381例,使用简明国际神经精神访谈诊断精神障碍并评估自杀风险,精神症状维度评定量表(CRDPSS)评估症状,采用多因素logistic回归分析探讨3类精神障碍患者自杀风险的差异及相关因素。结果:37例(1.8%)精神分裂症患者、516例(57.1%)抑郁症患者、102例(26.8%)双相障碍患者近1个月有自杀风险。与精神分裂症患者相比,抑郁症(OR=36.50)和双相障碍患者(OR=20.10)自杀风险增加。女性(OR=1.87)、目前吸烟(OR=1.76)、有自杀家族史(OR=5.09)、CRDPSS幻觉条目得分高(OR=1.80)、CRDPSS抑郁条目得分高(OR=1.54)是患者有自杀风险的危险因素。结论:抑郁症和双相障碍患者的自杀风险高于精神分裂症患者,临床上应定期评估患者的自杀风险,重点关注存在幻觉和抑郁症状的患者。
Objective:To describe and analyze suicide risk of patients with schizophrenia,major depressive disorder,and bipolar disorder.Methods:A total of 2016 patients with schizophrenia,903 patients with major de-pressive disorder,and 381 patients with bipolar disorder from inpatients,clinics,or communities who met the diag-nostic criteria of the Diagnostic and Statistical Manual of Mental Disorders,Fifth Edition were recruited.All patients were interviewed by psychiatrists using the Mini International Neuropsychiatric Interview to diagnose mental disor-ders and assess suicide risk,as well as Clinical-Rated Dimensions of Psychosis Symptom Severity(CRDPSS)to as-sess symptoms.Differences and risk factors of suicide risk among three types of mental disorders were explored u-sing multivariate logistic regression analysis.Results:In the past one month,37 patients with schizophrenia(1.8%),516 patients with major depressive disorder(57.1%),and 102 patients with bipolar disorder(26.8%)had suicide risk.Compared with patients with schizophrenia,suicide risk in patients with major depressive disorder(OR=36.50)and bipolar disorder(OR=20.10)increased.Female(OR=1.87),smoking(OR=1.76),family history of suicide(OR=5.09),higher score of CRDPSS hallucination(OR=1.80),and higher score of CRDPSS depression(OR=1.54)were risk factors of suicide risk of patients.Conclusions:Suicide risk of patients with ma-jor depressive disorder and bipolar disorder is higher than that of patients with schizophrenia.In clinical practice,it is important to regularly assess suicide risk of patients.Patients who experience symptoms of hallucination and de-pression should be paid more attention to.
作者
罗传琳
李媛媛
刘肇瑞
何燕玲
周亮
刘波
章杰
龚元东
刘燕
卢瑾
周艳萍
高长青
董青
蔡德芳
杨润许
张婷婷
黄悦勤
LUO Chuanlin;LI Yuanyuan;LIU Zhaorui;HE Yanling;ZHOU Liang;LIU Bo;ZHANG Jie;GONG Yuandong;LIU Yan;LU Jin;ZHOU Yanping;GAO Changqing;DONG Qing;CAI Defang;YANG Runxu;ZHANG Tingting;HUANG Yueqin(The Second People's Hospital of Pu'er,Pu'er 665000,Yunnan Province,China;Peking University Sixth Hospital,Peking Uni-versity Institute of Mental Health,NHC Key Laboratory of Mental Health(Peking University),National Clinical Research Center for Mental Disorders(Peking University Sixth Hospital),Beijing 100083,China;Shanghai Mental Health Centre,Shanghai 200030,China;The Affiliated Brain Hospital of Guangzhou Medical University,Guangzhou 510370,China;Jingzhou Mental Health Center,Jingzhou 434000,Hubei Province,China;The Third People's Hospital of Zhongshan,Zhongshan Mental Health Center,Zhongshan 528451,Guangdong Province,China;Shandong Mental Health Center,Jinan 250014,China;Jining Medical University,Jining 272013,Shandong Province,China;The First Affiliated Hospital of Kunming Medical University,Kunming 650032,China;The Mental Hospital of Yunnan Province,Kunming 650224,China;Chuxiong Yi Autonomous Prefecture Peo-ple's Hospital of the Second,Chuxiong 675000,Yunnan Province,China;The Second People's Hospital of Yuxi City,Yuxi653100,YunnanProvince,China)
出处
《中国心理卫生杂志》
CSCD
北大核心
2024年第1期1-8,共8页
Chinese Mental Health Journal
基金
国家重点研发计划(2017YFC0907800)。
关键词
精神分裂症
抑郁症
双相障碍
自杀
精神病性症状
schizophrenia
major depressive disorder
bipolar disorder
suicide
psychotic symptoms
