摘要
本文基于缺铁性贫血(IDA)对近年补铁剂的开发与应用研究展开综述,为补铁剂的研发与临床选择提供新思路。重点介绍了IDA不同阶段、补铁剂型选择、适应证及不良反应等,并对一些处于临床研究阶段的补铁剂进行了介绍。随着抗贫血研究的深入,研究热点将聚焦于利用植物、微生物及海洋生物等资源,有望开发出用药更安全、吸收利用度更高、起效更快的新型补铁剂。
This paper reviews the development and application of iron supplements based on iron deficiency anemia(IDA)in recent years,providing new ideas for the development and clinical selection of iron supplements.The different stages of IDA,the selection of types of iron supplements,indications and adverse reactions are mainly introduced.Some iron supplements in the stage of clinical research are also introduced.With the development of anti-anemia research,the research hotspots will focus on the utilization of plants,microorganisms and marine organisms,and other resources,and it is expected to develop a new iron supplement with safer medication,higher absorption and utilization,and faster onset time.
作者
马玉颖
吴海
杨铁虹
MA Yuying;WU Hai;YANG Tiehong(College of Pharmacy,Shaanxi University of Chinese Medicine,Xianyang 712046,China;China National Pharmaceutical Group Southwest Medicine Co.,Ltd,Chengdu 610045,China;Department of Medicinal Chemistry and Pharmaceutical Analysis,School of Pharmacy,Air Force Medical University,Xi'an 710032,China)
出处
《空军军医大学学报》
CAS
2023年第12期1225-1228,共4页
Journal of Air Force Medical University
基金
国家自然科学基金(31671015)。
关键词
缺铁
缺铁性贫血
口服补铁剂
静脉补铁剂
iron deficiency
iron deficiency anemia
oral iron supplements
intravenous iron supplements