摘要
Whether the alternated microbiota in the gut contribute to the risk of allograft rejection(AR)and pulmonary infection(Pl)in the setting of lung transplant recipients(LTRs)remains unexplored.A prospective multicenter cohort of LTRs was identified in the four lung transplant centers.Paired fecal and serum specimens were collected and divided into AR,Pl,and event-free(EF)groups according to the diagnosis at sampling.Fecal samples were determined by metagenomic sequencing.
基金
This work was supported by the National Key Research and Development Program of China(2022YFC2504800)
National Natural Science Foundation of China(Nos.82072257 and 82202543)
Scientific and Technological Innovation action Plan of Science and Technology Commission of Shanghai Municipality(Nos.20DZ2253700,20DZ2272000,21410750500,and 22Y21900500)
Shanghai Municipal Health Commission(shslczdzk01001)
Guangxi Department of Science and Technology Foundation(No.2020GXNSFGA238001).
