摘要
目的 分析负压创面疗法(negative pressure wound therapy, NPWT)联合银离子水凝胶敷料治疗糖尿病足(diabetic foot, DF)溃疡的效果。方法 选择2021年1月-2022年1月期间泉州市正骨医院收治的DF溃疡患者60例为研究对照,采用随机数表法分为对照组(n=30)与研究组(n=30)。两组患者均接受常规治疗,对照组清创后应用银离子水凝胶敷料,研究组在此基础上应用NPWT技术。针对两组患者的临床疗效、白细胞介素-6(interleukin-6,IL-6)、白细胞介素-1β(interlenkin-1β,IL-1β)与C反应蛋白(C-reactiveprotein,CRP)水平,以及溃疡治愈时间、换药次数及住院时间进行比较。结果 治疗的总有效率比较中,研究组结果较对照组高,差异有统计学意义(P<0.05)。治疗后,研究组IL-6、IL-1β、CRP指标低于对照组,差异有统计学意义(P<0.05)。研究组溃疡治愈时间、住院时间均短于对照组,换药次数少于对照组,差异有统计学意义(P<0.05)。结论 NPWT联合银离子水凝胶敷料治疗DF溃疡效果确切,能够有效抑制炎症因子,减少换药次数,加快康复进程。
Objective To analyze the effect of negative pressure wound therapy(NPWT)combined with silver ion hy-drogel dressing on diabetic foot ulcers(DF).Methods 60 patients with DF ulcer admitted to Quanzhou Bone-setting Hospital from January 2021 to January 2022 were selected as the study control,and were divided into control group(n=30)and study group(n=30)by random number table method.Both groups received conventional treatment,the con-trol group was treated with silver ion hydrogel dressing after debridement,and the study group was treated with NPWT technology on the basis of this.The clinical efficacy,interleukin-6(IL-6),interlenkin-1β(IL-1β)and C-reactive protein(CRP)levels of the two groups of patients were investigated.Ulcer healing time,dressing change times and hos-pital stay were compared.Results The total effective rate of the study group was higher than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the indexes of IL-6,IL-1βand CRP in the study group were lower than those in the control group,and the difference was statistically significant(P<0.05).The ul-cer healing time and hospitalization time of the study group were shorter than those of the control group,and the dress-ing changes was less than that of the control group,the difference was statistically significant(P<0.05).Conclusion NPWT combined with silver ionized hydrogel dressing is effective in treating DF ulcer,which can effectively inhibit inflammatory factors,reduce the number of dressing changes,and accelerate the rehabilitation process.
作者
余珍华
魏彩虹
徐惠珠
YU Zhenhua;WEI Caihong;XU Huizhu(Quanzhou Bone-setting Hospital,Quanzhou,Fujian Province,362019 China)
出处
《糖尿病新世界》
2023年第17期16-19,共4页
Diabetes New World Magazine
基金
福建省漳州市自然科学基金(ZZ2017J03)。
关键词
负压创面疗法
银离子水凝胶敷料
糖尿病足溃疡
Negative pressure wound therapy
Silver ion hydrogel dressing
Diabetic foot ulcer
