摘要
儿童炎症性肠病(PIBD)是一组病因不明的慢性复发性非特异性肠道炎症性疾病,发病机制复杂,目前在诊断和治疗方面仍然面临挑战。近年来,儿童IBD在国内外的发病率呈现上升趋势,引起了儿科医师的广泛关注。文章在儿童IBD发病机制进展、最佳治疗目标的监测策略、治疗方法进展、青春期IBD管理及向成人转诊过渡衔接等方面进行了总结,旨在为我国儿科医师IBD的研究提供参考。
Pediatric inflammatory bowel disease(PIBD)refers to a group of chronic and recurrent intestinal inflammatory diseases with unidentified cause.The complexity of its pathogenesis presents ongoing challenges in diagnosis and treatment.In recent years,there has been a noticeable increase in the prevalence of IBD among children both domestically and internationally,which has aroused widespread concern among pediatricians.This article aims to provide a comprehensive overview of the pathogenesis in pediatric IBD,a turbo-charged treat to target strategy in IBD,as well as the transition of management in adolescents with IBD.Its findings can serve as a valuable reference for Chinese pediatricians engaged in IBD research.
作者
吴捷
张添卓
WU Jie;ZHANG Tianzhuo(Department of Gastroenterology,Beijing Children's Hospital,Capital Medical University,National Center for Children's Health,Beijing 100045,China)
出处
《临床儿科杂志》
CAS
CSCD
北大核心
2023年第11期801-807,共7页
Journal of Clinical Pediatrics
基金
国家重点研发计划(No.2022YFC2703603)
首都卫生发展科研专项(No.2022-2-2094)
北京市医院管理中心“登峰”人才培养计划(No.DFL20221003)。
关键词
儿童
炎症性肠病
发病机制
达标治疗
青春期转诊过渡
pediatric
inflammatory bowel disease
pathogenesis
treat to target
transition of management
