摘要
行为变异型额颞叶痴呆是以行为及人格改变为主要临床特征的神经变性疾病,是一种具有高度遗传性的临床异质性综合征,是额颞叶痴呆中最常见的一种类型,由于缺乏认识以及与精神疾病的重叠,往往存在误诊及漏诊,本文主要从遗传学、临床表现和鉴别诊断介绍行为变异型额颞叶痴呆相关研究进展,重点关注的是提高诊断的准确性及处理问题症状的策略。
Behavioral variant frontotemporal dementia is a neurodegenerative disease with behavioral and personality changes as the main clinical features.It is a clinically heterogeneous syndrome with a high degree of heritability,and is the most common type of frontotemporal dementia,which is often misdiagnosed and underdiagnosed due to a lack of awareness and overlap with psychiatric disorders.This article describes the advances in the research related to behavioral variant frontotemporal dementia from the perspectives of genetics,clinical manifestations,and differential diagnosis,with an emphasis on improving the accuracy of the diagnosis and the strategies for managing problematic symptoms.
作者
杨霞
纪勇
Xia YANG;Yong JI(Department of neurology,Beijing Tiantan Hospital,Capital Medical University,China National Clinical Research Center for Neurological Diseases,Beijing,China.;Department of Neurology,Tianjin Dementia Institute,Tianjin Key Laboratory of Cerebrovascular and Neurodegenerative Diseases,Tianjin Huanhu Hospital,Tianjin,China.)
出处
《阿尔茨海默病及相关病杂志》
2023年第3期249-252,共4页
Chinese Journal of Alzheimer's Disease and Related Disorders
关键词
额颞叶痴呆
认知
精神疾病
Frontotemporal dementia
Cognitive
Psychiatric disorders
