摘要
目的:探讨超声衰减成像(ATI)诊断不同程度肝脏脂肪变性的价值。方法:招募145例受试者进行前瞻性研究,以受控衰减成像(CAP)为参考标准,分析衰减系数值(ATI值)与受控衰减参数值(CAP值)的相关性,以及ATI诊断不同程度肝脏脂肪变性的效能。结果:ATI值与CAP值呈强正相关(r=0.915,P<0.000 1)。ATI值随肝脏脂肪变性程度的增加而增加,不同程度肝脏脂肪变性ATI值比较,差异均有统计学意义(均P<0.001)。以CAP作为参考标准,ATI诊断≥S1、≥S2、S3级肝脏脂肪变性的最佳阳性界值分别0.62、0.68、0.79 dB·cm^(-1)·MHz^(-1)。结论:ATI可无创定量诊断肝脏脂肪变性,有较高的诊断效能,且ATI值与CAP值呈强相关性。
Objective:To investigate the value of the ultrasound attenuation imaging(ATI)technique for diagnosing different degrees of liver steatosis.Methods:A total of 145 subjects were recruited for a prospective study.Using controlled attenuation imaging(CAP)as reference standard,the correlation between ATI value and CAP value was analyzed,and the efficacy of ATI in diagnosing different degrees of hepatic steatosis was analyzed.Results:A strong positive correlation was demonstrated between ATI value and CAP value(r=0.915,P<0.0001).The mean value of ATI increased with the degree of liver steatosis,and the difference in the mean value of ATI between different degrees of liver steatosis was statistically significant(P<0.001).Using CAP as a reference standard,the best positive predictive values of ATI for diagnosing≥S1,≥S2,and S3 were 0.62,0.68,and 0.79 dB·cm-1·MHz-1,respectively.Conclusions:ATI is a good noninvasive quantitative diagnostic method of hepatic steatosis.It is highly efficient in the diagnosis of steatosis and has a strong correlation with CAP.
作者
王丹
连溯
龙富立
伍业冬
莫秋艳
彭子明
梁春燕
周庆锋
陆斌
刘雪玲
WANG Dan;LIAN Shuo;LONG Fuli;WU Yedong;MO Qiuyan;PENG Ziming;LIANG Chunyan;ZHOU Qingfeng;LU Bin;LIU Xueling(Department of Ultrasound,First Affiliated Hospital of Guangxi University of Chinese Medicine,Nanjing 530023,China)
出处
《中国中西医结合影像学杂志》
2023年第5期531-535,共5页
Chinese Imaging Journal of Integrated Traditional and Western Medicine
基金
国家自然科学基金(81760844)
广西壮族自治区中医药局自筹课题(GZZC2019056)
广西医疗卫生适宜技术开发与推广项目(S2019022)
广西中医药大学校级面上项目(2019MS028)
广西壮族自治区卫健委自筹课题(Z20200741,Z-A20230913)。
关键词
衰减成像
受控衰减成像
肝脏脂肪变性
超声检查
Attenuation imaging
Controlled attenuation imaging
Hepatic steatosis
Ultrasonagraphy
