摘要
目的分析组织胶疗法辅助治疗肝硬化致食管胃底静脉曲张破裂出血的效果及安全性。方法选取2019年2月至2020年11月本院收治的73例肝硬化致食管胃底静脉曲张破裂出血患者作为研究对象,采用奇偶数分组法分为对照组(n=36)与观察组(n=37)。对照组采用内镜下套扎术并注射聚桂醇治疗,研究组采用内镜下套扎术及组织胶治疗,比较两组临床疗效、止血效果、治疗次数及时间、并发症发生情况。结果观察组治疗总有效率为97.30%,高于对照组的77.78%,差异有统计学意义(P<0.05)。两组止血成功率比较差异无统计学意义;观察组再出血率低于对照组,差异有统计学意义(P<0.05)。研究组治疗次数少于对照组,治疗时间短于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率明显低于对照组,差异有统计学意义(P<0.05)。结论组织胶疗法辅助治疗肝硬化致食管胃底静脉曲张破裂出血的效果显著,可明显降低患者再出血率及并发症发生率,减少治疗次数,缩短治疗时间,值得临床推广应用。
Objective To analyze the efficacy and safety of tissue glue therapy as an adjuvant treatment for esophageal and gastric variceal bleeding caused by liver cirrhosis.Methods 73 patients with esophageal and gastric variceal bleeding caused by liver cirrhosis admitted to our hospital from February 2019 to November 2020 were selected as the study subjects,and they were divided into the control group(n=36)and the observation group(n=37)using an odd even number grouping method.The control group was treated with endoscopic ligation and injection of paclitaxel,while the observation group was treated with endoscopic ligation and tissue glue,the clinical efficacy,hemostatic effect,treatment frequency and time,and incidence of complications were compared between the two groups.Results The total effective rate in the observation group was 97.30%,which was higher than 77.78%in the control group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in the success rate of hemostasis between the two groups;the rebleeding rate in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).The treatment frequency of the research group was less than that in the control group,and the treatment time was shorter than that in the control group,and the difference was statistically significant(P<0.05).The incidence of complications in the observation group was significantly lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Tissue glue therapy has significant effect on the treatment of esophageal and gastric variceal bleeding caused by liver cirrhosis,it can significantly reduce the incidence of rebleeding and complications,reduce treatment frequency,shorten treatment time,and is worthy of clinical promotion and application.
作者
徐国峰
蒋大亮
范琳峰
XU Guofeng;JIANG Daliang;FAN Linfeng(Department of Gastroenterology,First Affiliated Hospital of Jiangxi Medical College,Ganzhou,Jiangxi,341000,China;Department of Gastrointestinal Surgery,First affiliated Hospital of Jiangxi Medical College,Ganzhou,Jiangxi,341000,China)
出处
《当代医学》
2023年第17期57-60,共4页
Contemporary Medicine
关键词
肝硬化
食管胃底静脉曲张破裂出血
组织胶疗法
安全性
Liver cirrhosis
Esophageal and gastric variceal bleeding
Tissue glue therapy
Security
