摘要
目的探究牙髓血运重建术治疗年轻恒牙根尖周病变效果及对疼痛情况影响。方法选取2019年2月至2020年2月本院收治的95例年轻恒牙根尖周病变患者作为研究对象,随机分为对照组(n=47)与观察组(n=48)。对照组行根尖诱导成形术治疗,观察组行牙髓血运重建术,比较两组临床疗效、治疗前后牙根生长情况、疼痛程度[视觉模拟评分法(VAS)]、炎症因子水平和并发症发生情况。结果观察组治疗总有效率为95.83%,高于对照组的78.72%,差异有统计学意义(P<0.05)。治疗前,两组牙根生长情况和疼痛程度比较差异无统计学意义;治疗后,两组根管壁厚度均厚于治疗前,牙冠根比均高于治疗前,VAS评分均低于治疗前,且观察组根管壁厚度厚于对照组,牙冠根比高于对照组,VAS评分低于对照组,差异有统计学意义(P<0.05)。治疗前,两组超敏C反应蛋白、肿瘤坏死因子-α、白细胞介素-4、白细胞介素-6水平比较差异无统计学意义;治疗后,两组超敏C反应蛋白、肿瘤坏死因子-α和白细胞介素-6水平均低于治疗前,白细胞介素-4水平均高于治疗前,且观察组超敏C反应蛋白、肿瘤坏死因子-α和白细胞介素-6水平低于对照组,白细胞介素-4水平高于对照组,差异有统计学意义(P<0.05)。观察组并发症发生率为6.25%,低于对照组的21.28%,差异有统计学意义(P<0.05)。结论牙髓血运重建术治疗年轻恒牙根尖周病变,疗效确切,可增加牙根长度和管壁厚度,明显缓解疼痛感,减少并发症发生,值得临床推广应用。
Objective To explore the effect of endodontic revascularization in the treatment of periapical lesions of young permanent teeth and its effect on pain conditions.Methods A total of 95 young patients with periapical permanent tooth lesions admitted to our hospital from February 2019 to February 2020 were selected as the research subjects,and they were randomly divided into the control group(n=47)and the observation group(n=48).The control group was treated with apical induction plasty,and the observation group was treated with pulp revascularization.The clinical efficacy,root growth,pain degree(visual analog scale[VAS]),levels of inflammatory factors before and after treatment and incidence of complications were compared between the two groups.Results The total effective rate in the observation group was 95.83%,higher than 78.72%in the control group,the difference was statistically significant(P<0.05).Before treatment,there were no significant differences in root growth and pain degree between the two groups;after treatment,the root canal wall thickness of the two groups were thicker than those before treatment,the tooth crown root ratio were higher than those before treatment,and the VAS scores were lower than those before treatment,the root canal wall thickness inthe observation group was thicker than that in the control group,the tooth crown root ratio was higher than that in the control group,and the VAS score was lower than that in the control group,the differences were statistically significant(P<0.05).Before treatment,there were no significant differences in the hypersensitive C-reactive protein,tumor necrosis factor-α,interleukin-4 and interleukin-6 levels between the two groups;after treatment,the levels of hypersensitive C-reactive protein,tumor necrosis factor-αand interleukin-6 of the two groups were lower than those before treatment,while the levels of interleukin-4 were higher than before treatment,and the levels of hypersensitive C-reactive protein,tumor necrosis factor-αand interleukin-6 in the observation group were lower than those in the control group,while the levels of interleukin-4 were higher than those in the control group,the differences were statistically significant(P<0.05).The incidence of complications in the observation group was 6.25%,lower than 21.28%in the control group,and the difference was statistically significant(P<0.05).Conclusion Endodontic revascularization is effective in the treatment of periapical lesions of young permanent teeth.It can increase the length of tooth root and the thickness of tube wall,relieve pain significantly and reduce complications,it is worthy of clinical promotion and application.
作者
韩蒙蒙
陈甜甜
郭庆敏
HAN Mengmeng;CHEN Tiantian;Guo Qingmin(Department of Stomatology,Zhanhua District Traditional Chinese Medicine Hospital,Binzhou,Shandong,256800,China;Department of Stomatology,Laizhou People's Hospital,Yantai,Shandong,261400,China)
出处
《当代医学》
2023年第10期130-133,共4页
Contemporary Medicine
关键词
牙髓血运重建术
根尖周病变
根管壁厚度
牙冠根比
疼痛程度
Endodontic revascularization
Periapical lesions
Root canal wall thickness
Crown root ratio
Degree of pain
