摘要
目的采用功能性近红外光谱(fNIRS)和表面肌电图(sEMG)探索动作观察(AO)、动作执行(AE)、动作模仿(AO+AE)3种基于镜像神经元系统(MNS)训练策略的运动控制机制。方法2022年7月至2023年2月,选择64例健康成年人,采用区组设计,完成单纯观看风景视频(对照)、观看风景视频时右手伸腕伸指(AE)、单纯观看右手伸腕伸指视频(AO)、观看右手伸腕伸指视频时右手伸腕伸指(AO+AE)4项任务,每项任务5个试次一组,随机出现不同的视频,循环8次,每次循环任务顺序随机。同步采用fNIRS采取左侧MNS各通道及感兴趣区(ROI)BA40、BA44、BA45、BA46、BA6、BA7的激活信号,采用sEMG检测指伸肌、桡侧腕伸肌的平均肌电值(AEMG)。结果与对照条件相比,AO、AE和AO+AE时均可诱发MNS激活,且强度呈递增趋势。与对照条件相比,AO时15个通道激活(q<0.05);AE时15个通道激活(q<0.05);AO+AE时20个通道全部激活(q<0.05);多数通道激活强度AO+AE>AE>AO。AO时,BA40、BA46、BA6和BA7共4个ROI激活(q<0.05);AE和AO+AE时,6个ROI均激活(q<0.05);多数ROI激活强度AO+AE>AE>AO。AO+AE时,指伸肌和桡侧腕伸肌的标准化AEMG均大于AE时(|t|>4.24,P<0.001)。结论动作观察、执行、模仿时,MNS系统均激活,且激活的范围和强度呈依次递增趋势。与动作执行相比,动作模仿时目标肌肉的激活更强。fNIRS同步sEMG可用于观察基于镜像神经元理论康复策略的神经机制研究。
Objective To explore the neuromuscular control mechanism of training strategies based on mirror neuron system(MNS):action observation(AO),action execution(AE)and action imitation(AO+AE)using functional Near Infrared Spectroscopy(fNIRS)and surface electromyography(sEMG).Methods From July,2022 to February,2023,64 healthy adults were asked to finish four tasks:watching landscape video(control),watching landscape video and acting right wrist and hand extension(AE),watching right wrist and hand extension video(AO),and watching right wrist and hand extension video and acting right wrist and hand extension(AO+AE).A block design was adopted,five times a task in a block,eight cycles,random orders in videos and tasks.The activation of each channel and regions of interest(ROI,namely BA40,BA44,BA45,BA46,BA6 and BA7)in left MNS regions was detected with fNIRS synchronously,as well as the average electromyography(AEMG)of extensor digitorum and extensor carpi radialis with sEMG.Results Compared with the control condition,MNS activated in AO,AE and AO+AE conditions,and the intensities mildly increased in turn.Compared with the control condition,15 channels activated in AO condition,15 channels activated in AE condition,and all 20 channels activated in AO+AE condition;and the activation intensities of most channels were AO+AE>AE>AO.Four ROI,BA40,BA46,BA6 and BA7,activated in AO condition,all the six ROI activated in AE and AO+AE conditions,and the activation intensities of most ROI were AO+AE>AE>AO.The standardized AEMG of extensor digitorum and extensor carpi radialis were higher in AO+AE condition than in AE condition(|t|>4.24,P<0.001).Conclusion MNS has been activated during action observation,execution and imitation,and the ranges and intensities of activation increase in turn.The target muscles activate more during imitation than during execution.Synchronous application of fNIRS and sEMG is feasible in the study of neural mechanism of rehabilitation strategies based on mirror neuron theory.
作者
崔尧
丛芳
黄富表
曾明
颜如秀
CUI Yao;CONG Fang;HUANG Fubiao;ZENG Ming;YAN Ruxiu(Capital Medical University School of Rehabilitation Medicine,Beijing 100068,China;Beijing Bo'ai Hospital,China Rehabilitation Research Center,Beijing 100068,China;The Second Hospital of Jiaxing City,Jiaxing,Zhejiang 314000,China)
出处
《中国康复理论与实践》
CSCD
北大核心
2023年第7期782-790,共9页
Chinese Journal of Rehabilitation Theory and Practice
基金
首都卫生发展科研专项项目青年优才项目(No.首发2022-4-6014)
中国康复研究中心科研基金项目青年基金项目(No.2021ZX-Q8)。
关键词
镜像神经元
功能性近红外光谱
表面肌电图
运动功能
神经机制
mirror neuron
functional near infrared spectroscopy
surface electromyography
motor function
neural mechanism
