摘要
目的了解2020—2022年上海市急性呼吸道感染(ARI)病例中病毒病原学构成和流行规律,为呼吸道疾病的防控提供数据支持。方法以2020—2022年上海市监测哨点医院采集的4325例ARI病例标本为研究对象,利用多重聚合酶链式反应进行常见呼吸道病原体的检测,采用Excel 2211和SPSS 22.0软件对病毒检出结果进行统计分析。结果4325例ARI病例病毒检出率为17.80%(770,770/4325),冬季为病毒感染的高峰季节。2020年检出率最高的病毒为鼻病毒/肠道病毒(HRV/HEV),2021—2022年检出率最高的为乙型流感病毒(FluB);流感病毒(IFV)、人偏肺病毒(hMPV)感染高峰在冬春两季,呼吸道合胞病毒(RSV)和副流感病毒(PIV)感染高峰在秋冬两季,全年都可观察HRV/HEV流行,腺病毒(ADV)和人博卡病毒(HBoV)没有明确的流行趋势;IFV是青年和中老年组ARI病例中最常检出的病毒,老年组中HRV/HEV检出率最高。结论FluB和HRV/HEV是2020—2022年上海市成年人ARI病例中主要流行病毒病原体,不同呼吸道病毒的流行情况存在年龄和时间差异,应持续加强ARI病例的病原学监测。
Objective To investigate the etiological and epidemiological characteristics of acute respiratory infections(ARIs)in adults in Shanghai from 2020 to 2022 and provide evidence for the effective prevention and control of acute respiratory tract infection.Methods Basic information and respiratory tract samples of 4325 ARI cases were collected from sentinel hospitals in Shanghai during 2020-2022.Respiratory viruses were detected by multiple fluorescence quantitative polymerase chain reaction(PCR),and the results were statistically analyzed using software Excel 2211 and IBM SPSS Statistics 22.0.Results The overall positive rate of respiratory viruses in 4325 samples was 20.72%(896/4325).The incidence peak of respiratory viral infection occurred in winter.The virus with the highest detection rate was rhinovirus/enterovirus(HRV/HEV)in 2020,and influenza B virus during 2021-2022.The detection rates of influenza viruses and human metapneumovirus(hMPV)were higher in winter and spring.The detection rates of respiratory syncytial virus(RSV)and parainfluenza virus(PIV)were higher in autumn and winter.HRV/HEV infection could be observed throughout the year.While there was no significant differences in the detection rates of human coronavirus(HCoV),adenovirus(ADV)and human Boca virus(HBoV)among different seasons.Influenza virus was the most frequently detected virus in ARI cases in young and middle-aged or elderly adults,and the detection rate of HRV/HEV was highest in the elderly group.Conclusion Influenza B virus and HRV/HEV were the main viral pathogens of ARI,and the epidemiological characteristics of infections of different respiratory viruses varied in different age groups and seasons.Specific etiological surveillance and control strategies should be taken in the future.
作者
刘嘉婧
邱琪
张万菊
周艳秋
孔德川
崔晓青
郑雅旭
张曦
滕峥
Liu Jiajing;Qiu Qi;Zhang Wanju;Zhou Yanqiu;Kong Dechuan;Cui Xiaoqing;Zheng Yaxu;Zhang Xi;Teng Zheng(Shanghai Municipal Center for Disease Control and Prevention,Shanghai 200336,China)
出处
《疾病监测》
CAS
CSCD
北大核心
2023年第7期792-798,共7页
Disease Surveillance
基金
上海市公共卫生建设三年行动计划(No.GWV-2)。
关键词
急性呼吸道感染
呼吸道病毒
监测
Acute respiratory infection
Respiratory virus
Surveillance
