摘要
目的探究壳聚糖口腔溃疡凝胶治疗轻型复发性阿弗他溃疡(RAU)的局部临床疗效。方法选取2021年3月至2022年3月该院收治的轻型RAU患者86例,采用随机数字表法分为病例组(47例)和对照组(39例)。病例组局部给予壳聚糖口腔溃疡凝胶联合复方氯己定含漱液治疗,对照组局部仅使用复方氯己定含漱液治疗。2组患者均全身给予维生素C片联合复合维生素B片治疗。观察2组患者治疗前后临床疗效。结果病例组患者用药后第3、5、7天总有效率分别为68.1%(32/47)、83.0%(39/47)、93.6%(44/47);对照组患者用药后第3、5、7天总有效率分别为38.5%(15/39)、51.2%(20/39)、76.9%(30/39),2组患者用药后第3、5、7天总有效率比较,差异均有统计学意义(P<0.05)。结论壳聚糖口腔溃疡凝胶在治疗轻型RAU中具有明显临床疗效,能促进溃疡愈合并减轻患者疼痛感。
Objective To evaluate the local clinical effect of chitosan oral ulcer gel in the treatment of mild recurrent aphthous ulcer(RAU).Methods A total of 86 patients with mild RAU admitted to this hospital from March 2021 to March 2022 were divided into the case group(47 cases)and the control group(39 cases)by random number table method.The patients in the case group were given chitosan oral ulcer gel and compound chlorhexidine gargle locally,while the control group was only given compound chlorhexidine gargle locally.The subjects in both groups were given vitamin C tablets and compound vitamin B tablets.The local clinical effects of the two groups were observed before and after treatment.Results In the case group,the total effective rates were 68.1%(32/47),83.0%(39/47)and 93.6%(44/47)on the 3rd,5th and 7th day after medication,respectively.In the control group,the total effective rates of the corresponding days were 38.5%(15/39),51.2%(20/39),76.9%(30/39),respectively,the differences were statistically significant(P<0.05).Conclusion Chitosan oral ulcer gel has a significant clinical effect in the treatment of mild recurrent aphthous ulcer,which can promote ulcer healing and relieve the pain in patients.
作者
李丽娜
杨晓琴
马蓉
LI Lina;YANG Xiaoqin;MA Rong(General Hospital of Ningxia Medical University,Yinchuan,Ningxia 750000,China)
出处
《现代医药卫生》
2023年第14期2396-2399,2406,共5页
Journal of Modern Medicine & Health
