摘要
新型冠状病毒(SARS-CoV-2)感染导致的新型冠状病毒肺炎(COVID-19)自爆发以来,迅速肆虐全球并导致数以亿计的感染人数。COVID-19的早期诊断有利于病毒传播的控制以及患者的及时救治。影像技术中,胸部CT是COVID-19诊断和评估的重要依据。虽然一般不推荐^(18)F-FDG PET作为COVID-19的常规诊断手段,但基于PET全身多系统性扫描和功能性影像诊断的特点,^(18)F-FDG PET技术在SARS-CoV-2相关事件评估中发挥了重要作用。该文通过文献调研及临床报告分析,汇总了^(18)F-FDG PET在COVID-19诊断、预后评估与长期后遗症评估中的应用价值及SARS-CoV-2疫苗注射后^(18)F-FDG PET临床表现,展望了其他核医学新型分子探针在COVID-19中的应用及发展方向。
Coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)has rapidly ravaged the world and infected hundreds of millions of people since its outbreak.Early diagnosis of COVID-19 is conducive to the control of virus transmission and the timely treatment of patients.Among the imaging techniques,chest CT is an important basis for the diagnosis and evaluation of COVID-19.^(18)F-FDG PET is not generally recommended as a routine diagnostic tool for COVID-19,but it plays an important role in the assessment of SARS-CoV-2-related events based on the characteristic of whole-body multi-systemic scan and functional imaging diagnosis.In this paper,the application of^(18)F-FDG PET in COVID-19 diagnosis,prognostic evaluation and long-term sequelae evaluation,and clinical performance of ^(18)F-FDG PET after COVID-19 vaccine are summarized on the basis of literature research and clinical reports analysis.Furthermore,the application and development direction of other new molecular probes for nuclear medicine in COVID-19 are prospected.
作者
李葇
张岚
李丹妮
左长京
李潇
Li Rou;Zhang Lan;Li Danni;Zuo Changjing;Li Xiao(Department of Nuclear Medicine,Changhai Hospital,Navy Medical University,Shanghai 200433,China;Department of Applied Chemistry,Shanghai Institute of Applied Physics,Chinese Academy of Sciences,Shanghai 201800,China)
出处
《中华核医学与分子影像杂志》
CAS
CSCD
北大核心
2023年第7期429-432,共4页
Chinese Journal of Nuclear Medicine and Molecular Imaging
基金
国家自然科学基金(82272040)。
