摘要
目的统计贵州中医药大学第一附属医院细辛的使用情况,并统计古医籍《伤寒论》与《金贵要略》中含细辛的方剂用量及主治,分析医院细辛的常用剂量与药典相比超剂量使用的比例、与古医籍中对细辛用量及主治对比。方法采用回顾性分析,统计2021年该院门诊使用细辛的所有处方,对患者的性别、年龄,每付中药使用的味数、剂数、所用细辛的剂量,与细辛常用的配伍,常用的证型等相关资料进行统计和分析;对古医籍中细辛用量及主治进行总结。结果患者14971例,男6091例,女8880例,女性患者约为男性患者的1.46倍,患者年龄0~10岁居多。从科室分布看,专家诊室开具的处方占比最高,达9.88%,其次是脑病科(神经内科),占比为9.32%。在药典规定的1~3 g细辛范围内使用11617张,超出剂量(4~30 g)使用范围3354张,处方中细辛剂量使用合格率为77.60%(11617/14971),整体符合药典规定。使用药物味数最少有1味,最多有55味。使用的药物味数集中在7~21味,处方数量为14274张,占所有含细辛门诊处方总数的95.34%。处方开具的剂数最少1剂,有165张。1~7剂的处方张数有12803张,占抽取总处方数14971张的85.52%。单张处方开具30剂以内的有14955张,占抽取总处方数14971张的99.89%。与细辛联合使用频率最高的药物是川芎;古医籍中细辛的使用剂量最高为六两,最低使用剂量为二分,其中常用量为三两,达9首。结论2021年医院开具的中药处方中,细辛使用的剂量整体符合药典规定,其用量远小于《伤寒杂病论》中的剂量。
Objective The usage of asarum in the First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine was analyzed,and the dosage and indications of asarum prescriptions contained in the ancient medical books Shanghan Lun and Jingui Yaolue were counted,and the proportion of overdosage of asarum used in the common dosage of asarum in the hospital was analyzed compared with the pharmacopoeia,and the dosage and indications of asarum used in the ancient medical books were compared.Methods By retrospective analysis,all prescriptions of asarum used in outpatient department of the hospital in 2021 were collected and analyzed.Related data such as gender and age of patients,the number of flavors and doses used in each payment of traditional Chinese medicine,dosage of asarum used,compatibility with asarum commonly used and syndrome types commonly used were analyzed statistically.The dosage and indications of asarum in ancient medical books were summarized.Results There were 14971 patients,including 6091 males and 8880 females.The number of female patients was about 1.46 times that of male patients,and the age of patients was mostly 0~10 years old.From the distribution of departments,the prescriptions issued by the expert consultation room accounted for the highest proportion,up to 9.88%,followed by the department of encephalopathy(neurology),accounting for 9.32%.11617 asarum tablets were used within the range of 1~3 g asarum prescribed by pharmacopeia,and 3354 tablets were used beyond the range of dosage(4~30 g).The qualified rate of asarum dosage was 77.60%(11617/14971),which was in line with the provisions of pharmacopeia.The number of drugs used was at least 1 flavor and at most 55 flavor.The number of drug flavors used mainly ranged from 7 to 21,and the number of prescriptions was 14274,accounting for 95.34%of all outpatient prescriptions containing asarum.At least one dose was prescribed,165 prescriptions.There were 12803 prescriptions with 1~7 doses,accounting for 85.52%of the total 14971 prescriptions.14955 prescriptions were issued within 30 doses,accounting for 99.89%of the total 14971 prescriptions.Ligusticum chuanxiong was the most frequently used drug combined with asarum;In ancient medical records,the highest dosage of asarum was six liang,and the lowest dosage was two fen,among them,the commonly used dosage was three liang,up to nine.Conclusion In the Chinese medicine prescription issued by the hospital in 2021,the dosage of asarum was generally in line with the pharmacopoeia provisions,and the dosage was far less than that in Shanghan Zabing Lun.
作者
陈艳
于佳
张宁
李广松
王欣欣
阮婧华
李玲
CHEN Yan;YU Jia;ZHANG Ning;LI Guangsong;WANG Xinxin;RUAN Jinghua;LI Ling(Department of Pharmacy,the First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine,Guiyang 550001,China)
出处
《临床合理用药杂志》
2023年第16期1-5,共5页
Chinese Journal of Clinical Rational Drug Use
基金
贵州省科技计划项目(黔科合LH字〔2017〕7145号)
贵州省“十四五”中医药、民族医药重点学科建设[QZYYZDXK(JS)-2021-03]
国家中医药管理局中药特色技术传承人才项目(国中医药办人教函〔2018〕204号)。
关键词
细辛
处方分析
临床使用
合理用药
Asarum
Prescription analysis
Clinical use
Rational drug use
