摘要
目的分析术中输血和心脏术后患者发生深静脉血栓(DVT)的关系。方法采用回顾性分析,以2020年1月至2022年1月期间来河南省胸科医院治疗的185例心脏手术患者为研究对象,依据患者是否发生DVT将其分为DVT组(n=34)和对照组(n=151)。对两组患者的各项一般资料和临床资料进行比较,对有统计学意义的因素进一步行Logistic多因素回归分析,探究心脏术后患者发生DVT的危险因素,并用Pearson分析术中输血与各危险因素的相关性。结果与对照组相比,DVT组患者的心脏病病程延长,原发性高血压、糖尿病、饮酒史、吸烟史、未使用抗血栓泵的发生率均升高,差异有统计学意义(P<0.05)。与对照组相比,DVT组患者的入院Lp水平、入院UA水平、入院Fbg水平、入院FDP≥35 mg/L、入院血红蛋白≤120 g/L、入院血小板计数/血红蛋白比值≥2.5、入院血糖≥8 mmol/L、术中输血、术后住院时间<7 d的发生率均升高,入院aPTT水平、入院PT水平均降低,差异有统计学意义(P<0.05)。合并糖尿病、未使用抗血栓泵、术中输血为心脏术后患者发生DVT的危险因素(P<0.05)。心脏手术患者的术中输血与合并糖尿病呈现正相关(P<0.05),与使用抗血栓泵呈现负相关(P<0.05)。结论合并糖尿病、未使用抗血栓泵、术中输血为心脏术后患者发生DVT的危险因素,且术中输血与DVT的发生存在相关性。
Objective To analyze the relationship between intraoperative blood transfusion and deep vein thrombosis(DVT)in patients after cardiac surgery.Methods A retrospective analysis was used to study 185 patients with cardiac surgery who came to our hospital from January 2020 to January 2022 as the research object.According to whether DVT occurred,the patients were divided into DVT group(n=34)and control group(n=151).The general and clinical data of the two groups were compared,and the statistically significant factors were further analyzed by Logistic multivariate regression analysis to explore the risk factors of DVT in patients after cardiac surgery,and the correlation between intraoperative blood transfusion and each risk factor was analyzed by Pearson.Results Compared with the control group,the course of heart disease in the DVT group was prolonged,and the incidence of essential hypertension,diabetes,drinking history,smoking history,and not using antithrombotic pump were increased,and the differences were statistically significant(P<0.05).Compared with the control group,the incidence of admission Lp level,admission UA level,admission Fbg level,admission FDP≥35 mg/L,admission hemoglobin<120 g/L,admission platelet count/hemoglobin ratio≥2.5,admission blood glucose≥8 mmol/L,intraoperative blood transfusion,and postoperative hospital stay<7 days were all increased in the DVT group.The levels of aPTT and PT on admission were significantly decreased(P<0.05).Diabetes mellitus,not using antithrombotic pump and intraoperative blood transfusion were risk factors for DVT in patients after cardiac surgery(P<0.05).Intraoperative blood transfusion was positively correlated with diabetes mellitus(P<0.05),and negatively correlated with the use of antithrombotic pump(P<0.05).Conclusion Diabetes mellitus,non-use of antithrombotic pump and intraoperative blood transfusion are risk factors for DVT in patients after cardiac surgery,and intraoperative blood transfusion is correlated with the occurrence of DVT.
作者
李艳凤
何发明
李晓召
曹向波
史博伦
何慧
晁珂
LIYan-feng;HE Fa-ming;LI Xiao-zhao(Department of Cardiac Surgery,Henan Thoracic Hospital Zhengzhou,Zhengzhou 450000,China)
出处
《中国实验诊断学》
2023年第5期533-537,共5页
Chinese Journal of Laboratory Diagnosis
基金
河南省医学科技攻关计划联合共建项目(LHGJ20220225)。
关键词
心脏手术
深静脉血栓
术中输血
危险因素
Cardiac surgery
Deep vein thrombosis
Intraoperative blood transfusion
Risk factors
