摘要
目的探讨高龄产妇妊娠期糖尿病(GDM)发生的相关危险因素。方法选择100例合并GDM高龄产妇患者为观察组,选择100例未合并GDM高龄产妇为对照组。收集、整理产妇资料,包括年龄、文化程度、孕产次、孕前体质量指数、日常运动量、每日睡眠时间、孕早期空腹血糖(FPG)水平、既往代谢疾病史等,对上述因素进行单因素分析,并对有差异的因素展开多因素logistic回归分析,以此分析高龄产妇发生GDM的相关危险因素。结果单因素分析显示:孕前体质量指数、日常运动量、每日睡眠时间、孕早期FPG水平与高龄产妇发生GDM有关(P<0.05);年龄、文化程度、孕产次、既往代谢疾病史、流产次数与高龄产妇GDM发生无关,差异无统计学意义;多因素分析显示:孕前体质量指数≥24 kg·m^(-2)、日常运动量<2 h/d、每日睡眠时间≤8 h/d、孕早期FPG水平≥6.1 mmol/L是高龄产妇发生GDM的高危因素(P<0.05)。结论孕前体质量指数≥24 kg·m^(-2)、日常运动量<2 h/d、每日睡眠时间≤8 h/d、孕早期FPG水平≥6.1 mmol/L是高龄产妇发生GDM的危险因素,临床需针对各危险因素制定具有针对性的干预措施,以减少GDM的发生。
Objective To explore risk factors associated with the development of gestational diabetes mellitus(GDM)in advanced maternal age.Methods 100 patients with combined GDM advanced maternal age were selected as the observation group,and 100 cases of advanced maternal age without comorbid GDM were selected as the control group.Maternal data were collected and sorted out,including age,education level,pregnancy and childbirth,gestational precursor body mass index,daily exercise volume,daily sleep time,fasting blood glucose(FPG)level in the first trimester of pregnancy,previous metabolic disease history,etc.Univariate analysis was conducted for the above factors,and multivariate logistic regression analysis was carried out for the different factors,so as to analyze the risk factors related to the occurrence of GDM in older women.Results Univariate analysis showed that the body mass index of gestational precursors,daily exercise,daily sleep time,and FPG levels in the first trimester were related to the occurrence of GDM in advanced maternal age,and the difference was statistically significant(P<0.05);age,education level,gestational birth,history of previous metabolic diseases,and the number of miscarriages were not related to the occurrence of GDM in advanced maternal age,and the difference was not statistically significant;multivariate analysis showed that the body mass index of precursors in pregnancy≥24 kg·m^(-2),daily exercise<2 h/d,daily sleep time≤8 h/d,first trimester FPG level≥6.1 mmol/L were high risk factors for GDM in advanced maternal age(P<0.05).Conclusion Gestational precursor body mass index≥24 kg·m^(-2),daily exercise<2 h/day,daily sleep time≤8 h/day,FPG level≥6.1 mmol/L in the first trimester are the risk factors for the development of GDM in advanced maternal age,and clinical interventions need to be tailored to each risk factor to reduce the occurrence of GDM.
作者
黄伟雯
姚碧云
李洪庆
HUANG Weiwen;YAO Biyun;LI Hongqing(Guangzhou Huadu District Maternal and Child Health Care Hospital(Huzhong Hospital),Guangzhou 510800,Guangdong,P.R.China;Guangzhou Huadu Tiangui Community Health Service Center,Guangzhou 510800,Guangdong,P.R.China)
出处
《滨州医学院学报》
2023年第3期189-192,共4页
Journal of Binzhou Medical University
关键词
妊娠期糖尿病
高龄产妇
危险因素
睡眠时间
日常运动量
gestational diabetes mellitus
advanced maternal age
risk factor
sleep time
daily exercise
