摘要
胰腺癌是消化系统常见肿瘤之一,具有临床症状隐匿、侵袭性强且易转移等特点,致死率高。近年来,免疫治疗在实体瘤治疗中开启新时代,但受胰腺癌肿瘤微环境影响,其在胰腺癌中的应用受到限制。笔者系统分析胰腺癌肿瘤微环境,总结胰腺癌免疫治疗相关临床研究,探讨胰腺癌免疫治疗未来方向。
Pancreatic cancer is one of the most common tumors in digestive system,which is characterized by insidious clinical symptoms,strong invasion,easy metastasis and high mortality.In recent years,immunotherapy is a new direction to the treatment of solid tumors,but its application in pancreatic cancer is limited by tumor microenvironment of pancreatic cancer.The authors systematically analyze the tumor microenvironment of pancreatic cancer,summarize the clinical researches related to pancreatic cancer immunotherapy,and discuss the prospect of pancreatic cancer immunotherapy.
作者
陈博滔
毛先海
Chen Botao;Mao Xianhai(Department of Hepatobiliary Surgery,Hunan Provincial People′s Hospital(the First Affiliated Hospital of Hunan Normal University),Changsha 410005,China)
出处
《中华消化外科杂志》
CAS
CSCD
北大核心
2023年第5期610-615,共6页
Chinese Journal of Digestive Surgery
基金
湖南省自然科学基金(2022JJ70015、2023JJ40371)。
