摘要
探索促进糖尿病皮肤伤口愈合的有效方法,是糖尿病治疗领域的重大需求。通过对中医药干预糖尿病皮肤伤口愈合的文献进行梳理,发现益气温阳活血和活血解毒类复方中药如疡愈涂剂、脑心通胶囊、复方黄柏液等可通过改善局部缺血缺氧、促进血管新生、促进肉芽组织生长等环节促进糖尿病患者皮肤的伤口愈合。多种中药有效成分及提取物如姜黄素、黄芪甲苷、槲皮素、银杏叶提取物等可通过抑制炎症反应和氧化应激、改善胰岛素抵抗、增加毛细血管新生等环节,促进糖尿病皮肤伤口愈合。
Exploring effective methods to promote wound healing is a major demand in the treatment of diabetes.By reviewing the literature about traditional Chinese medicine(TCM)for skin wound healing in patients with diabetes,it was found that TCM compounds with the function of boosting qi,warming yang and activating blood,as well as activating blood and resolve toxins,such as Yangyu Paint(疡愈涂剂),Naoxintong Capsule(脑心通胶囊),and Fufang Huangbai Liquid(复方黄柏液),can promote the wound healing of the skin of diabetic patients by improving local ischemia and hypoxia,promoting angiogenesis,and accelerating the growth of granulation tissue.A variety of active ingredients and extracts of Chinese medicinal,such as curcumin,astragalosideⅣ,quercetin,and ginkgo biloba extract,may promote wounds healing of diabetic skin by inhibiting inflammation and oxidative stress,improving insulin resistance,and increasing capillary neogenesis.
作者
史君鹤
曲华
何山
陆芳
SHI Junhe;QU Hua;HE Shan;LU Fang(Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing,100091;Wangjing Hospital,China Academy of Chinese Medical Sciences)
出处
《中医杂志》
CSCD
北大核心
2023年第10期1076-1080,共5页
Journal of Traditional Chinese Medicine
基金
中华中医药学会青年人才托举工程(2020-QNRC1-02)。
关键词
糖尿病
伤口愈合
糖尿病足
中医药疗法
diabetes
wound healing
diabetic foot
Chinese medicine therapy
