摘要
目的:分析甲状腺癌术后睡眠障碍的危险因素,建立列线图预测模型并评价其准确性。方法:选取2019年6月至2022年1月福建省肿瘤医院收治的甲状腺癌患者563例作为研究对象,按照时间顺序分为观察组(n=431)和对照组(n=132)。观察组为2019年6月至2021年7月收治的患者,对照组为2021年8月至2022年1月收治的患者。结果:观察组中,多因素分析结果表明年龄、术前焦虑、术后放射性碘治疗以及促甲状腺激素(TSH)抑制水平是睡眠障碍的独立危险因素,差异有统计学意义(P<0.05)。观察组和对照组的一致性指数(C-index)分别为0.771和0.758,校准曲线表明2组的预测结果与实际结果的一致性较好。结论:本研究建立的甲状腺癌术后睡眠障碍列线图模型具有较好的预测效能。
Objective:To analyze the risk factors of sleep disorders after thyroid cancer surgery,establish a nomograph prediction model and evaluate its accuracy.Methods:A total of 563 thyroid cancer patients admitted to Fujian Cancer Hospital from June 2019 to January 2022 were selected as the research subjects,and were divided into the observation group(n=431)and the control group(n=132)in chronological order.The observation group consisted of patients admitted from June 2019 to July 2021,while the control group consisted of patients admitted from August 2021 to January 2022.Results:In the observation group,the results of multifactor analysis showed that age,preoperative anxiety,postoperative radioiodine treatment and thyroid hormone(TSH)inhibition level were independent risk factors for sleep disorders,and the difference was statistically significant(P<0.05).The consistency index(C-index)of the observation group and the control group were 0.771 and 0.758,respectively.The calibration curve showed that the predicted results of the two groups had good consistency with the actual results.Conclusion:The nomograph model of postoperative sleep disorders in thyroid cancer established in this study has good predictive effectiveness.
作者
黄冰奇
邱艳华
陈英
安潇
叶钦
林丽英
何敏芬
林振孟
HUANG Bingqi;QIU Yanhua;CHEN Ying;AN Xiao;YE Qin;LIN Liying;HE Minfeng;LIN Zhenmeng(The Clinical Oncology School of Fujian Medical University/Department of Head and Neck Cancer Surgical Oncology Fujian Cancer Hospital,Fuzhou 350014,China)
出处
《世界睡眠医学杂志》
2023年第3期458-460,共3页
World Journal of Sleep Medicine
基金
福建省卫生健康科技计划项目(2021TG015)。
关键词
甲状腺癌
睡眠障碍
列线图
Thyroid cancer
Sleep disturbance
Nomogram
