摘要
目的分析总结文献中对乳腺增生、子宫肌瘤、甲状腺结节三病的中医证型和治则治法情况,挖掘三病中医辨证论治的关联性规律。方法检索中国期刊全文数据库(CNKI)、万方数据库和维普数据库自1990年1月-2020年6月收载的临床研究文献,将三病辨证论治的相关信息录入Excel 2010建立数据库,采用SPSS Statistics 22与SPSS Modeler 14.1进行频次、频率统计和关联规则分析。结果共计纳入文献346篇,其中乳腺增生151篇,子宫肌瘤100篇,甲状腺结节95篇。三病共有的中医证型为11种,其在乳腺增生、子宫肌瘤、甲状腺结节的占比分别为72.9%、35.07%、51.42%;三病共有的中医治法为18种,其在乳腺增生、子宫肌瘤、甲状腺结节的占比分别为73.91%、53.67%、56.21%。三病病位多在肝、脾、肾三脏及冲任二脉,主要证候要素为气滞、痰凝、血瘀;主要治疗八法为消法,其在乳腺增生、子宫肌瘤、甲状腺结节的占比分别为50.74%、56.25%、48.63%。关联规则显示三病证型均有肝郁气滞、血瘀、痰瘀互结证的强关联组合;治法均有疏肝理气、化痰散结、活血化瘀的强关联组合。结论三病在中医辨证论治上存在共性规律,符合中医“异病同治”的治疗原则,为进一步研究临床预防、诊断、治疗三病提供依据。
Objective To analyze and summarize the TCM syndrome types and treatment methods of mammary gland hyperplasia,uterine fibroids and thyroid nodules in the literature,and to explore the correlation law of TCM syndrome differentiation and treatment of the three diseases.Methods the clinical research literatures collected from CNKI,Wanfang database and VIP database from January 1990 to June 2020 were retrieved,and the related information on syndrome differentiation and treatment of the three diseases was input into Excel 2010 to establish the database.SPSS Statistics 22 and SPSS Modeler 14.1 were used for frequency and frequency Statistics and association rule analysis.Results A total of 346 literatures were included,including 151 cases of mammary hyperplasia,100 cases of uterine fibroids and 95 cases of thyroid nodules.There were 11 TCM syndromes in the three diseases,among which the proportion of hyperplasia of mammary gland,uterine fibroids and thyroid nodules were 72.9%,35.07% and 51.42%respectively.The three diseases were treated by 18 kinds of traditional Chinese medicine,which accounted for 73.91%,53.67% and 56.21% of mammary gland hyperplasia,uterine fibroids and thyroid nodules,respectively.The locations of the three diseases are mainly liver,spleen,kidney,Vital channel and Ren channel.The main syndromes of the three diseases are qi stagnation,spittoon and blood stasis.The eight main treatments were elimination,among which 50.74%were mammary gland hyperplasia,56.25% were uterine fibroids,and 48.63% were thyroid nodules.The association rules showed that all the syndromes of the three diseases had a strong association combination of liver stagnation and qi stagnation,blood stasis and phlegm-stasis.All the treatments have a strong combination of regulating liver and qi,resolving phlegm and dispersing knot,promoting blood circulation and removing stasis.Conclusion There are common rules in TCM syndrome differentiation and treatment of the three diseases,which accords with the TCM principle of "treating different diseases with same method",and provides a basis for further research on clinical prevention,diagnosis and treatment of the three diseases.
作者
江程
凌霄
李春晓
张莹莹
金艳涛
陈玉欢
陈萍
Jiang Cheng;Ling Xiao;Li Chunxiao;Zhang Yingying;Jin Yantao;Chen Yuhuan;Chen Ping(The Pharmacy of Henan University of TCM,Zhengzhou 450046,China;The First Afiliated Hospital of Henan University of TCM/Henan Province Engineering Research Center for Clinical Application,Evaluation and Transformation of TCM/Henan Key Laboratory of Clinical Pharmacy of Traditional Chinese Medicine,Zhengzhou 450000,China;Henan University of TCM of Cooperative Innovation Center for TCM Prevention and Treatment of Respiratory Diseases,Zhengzhou 450000,China)
出处
《世界科学技术-中医药现代化》
CSCD
北大核心
2023年第1期312-323,共12页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
河南省教育厅高等学校重点科研项目计划(19A360015):基于大数据挖掘的乳腺增生-子宫肌瘤-甲状腺结节三病的关联性研究及中医证型规律分析,负责人:李春晓
河南省中医管理局中医药科学研究重点专项(2018ZY1007):基于大数据挖掘的乳腺增生-子宫肌瘤-甲状腺结节三病间用药共性规律研究,负责人:李春晓
河南省卫生健康委员会中医药学科拔尖人才培养项目(豫卫中医函[2021]15号):河南省中医药传承与创新人才工程(仲景工程),负责人:李春晓。
关键词
乳腺增生
子宫肌瘤
甲状腺结节
证型
治则治法
关联规则
异病同治
Hyperplasia of mammary glands
Uterine fibroids
Thyroid nodules
Syndrome type
Rule of law
Association rules
Treating different diseases with same method
